Wei. Lu, et.al., Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder., Nature communications, 2014, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/25222142

Wei. Lu, et.al., Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder., Nature communications, 2014, 5

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• bradykinesia_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0005156IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• akinesia_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0002690IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• oxidative stress_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0003674IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• loss of dopaminergic neurons_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0003244IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• decreased dopamine level_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0005643IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• abnormal motor coordination/ balance_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001516IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• abnormal mitochondrion morphology_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0006035IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• short stride length_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001407IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• abnormal gait_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001406IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• abnormal mitochondrial crista morphology_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0011635IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• decreased vertical activity_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0002757IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• neuron degeneration_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0003224IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi
• abnormal mitochondrial physiology_Pgam5<tm1a(EUCOMM)Wtsi>/Pgam5<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0006036IC57BL6NPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsiPgam5tm1aEUCOMMWtsi