Kyung Soo. Park, et.al., Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response., Journal of immunology (Baltimore, Md. : 1950), 2014, 193

http://rdf.ncbi.nlm.nih.gov/pubmed/25238757

Kyung Soo. Park, et.al., Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response., Journal of immunology (Baltimore, Md. : 1950), 2014, 193

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ell2<tm1Cmil>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5897609
• Ell2<tm2.1Cmil>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5792877
• Ell2<tm1.1Cmil>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5790670

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired humoral immune response_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0020154I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• decreased IgA level_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm2.1Cmil>/Ell2<tm2.1Cmil>
  http://metadb.riken.jp/0001807I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm21CmilEll2tm21CmilEll2tm21CmilCd19tm1creCgnCd19
• decreased immunoglobulin level_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0002460I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• decreased plasma cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0008098I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• decreased IgG1 level_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm2.1Cmil>/Ell2<tm2.1Cmil>
  http://metadb.riken.jp/0008495I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm21CmilEll2tm21CmilEll2tm21CmilCd19tm1creCgnCd19
• decreased transitional stage T1 B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0009923I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• decreased transitional stage T3 B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0010228I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• increased pro-B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0008186I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• decreased mature B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0008211I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• decreased IgG1 level_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0008495I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• increased follicular B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0008173I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• increased immature B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0008214I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• increased pre-B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0003132I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• decreased transitional stage T2 B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0009926I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• decreased mature B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm2.1Cmil>/Ell2<tm2.1Cmil>
  http://metadb.riken.jp/0008211I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm21CmilEll2tm21CmilEll2tm21CmilCd19tm1creCgnCd19
• decreased IgM level_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0001806I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• decreased IgM level_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm2.1Cmil>/Ell2<tm2.1Cmil>
  http://metadb.riken.jp/0001806I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm21CmilEll2tm21CmilEll2tm21CmilCd19tm1creCgnCd19
• decreased IgA level_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0001807I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19
• decreased immunoglobulin level_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm2.1Cmil>/Ell2<tm2.1Cmil>
  http://metadb.riken.jp/0002460I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm21CmilEll2tm21CmilEll2tm21CmilCd19tm1creCgnCd19
• abnormal endoplasmic reticulum morphology_Cd19<tm1(cre)Cgn>/Cd19<+>,Ell2<tm1.1Cmil>/Ell2<tm1.1Cmil>
  http://metadb.riken.jp/0009378I129P2OlaHsd129S2SvPasC57BL6Cd19tm1creCgnCd19Ell2tm11CmilEll2tm11CmilEll2tm11CmilCd19tm1creCgnCd19

class

http://purl.org/net/cito/citesAsAuthority

• Ell2<tm1Cmil>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5897609
• Ell2<tm2.1Cmil>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5792877
• Ell2<tm1.1Cmil>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5790670