Sarah M. Turpin, et.al., Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance., Cell metabolism, 2014, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/25295788

Sarah M. Turpin, et.al., Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance., Cell metabolism, 2014, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cers6<tm1.1Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5607417
• Cers6<tm1Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5607416

class

http://purl.org/net/cito/citesAsAuthority

• Cers6<tm1.1Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5607417
• Cers6<tm1Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5607416

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased fat cell size_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0009269IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• abnormal ceramide level_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0012232IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• enhanced lipolysis_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0008034IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• abnormal cellular respiration_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0010954IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• increased energy expenditure_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0004889IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• decreased susceptibility to diet-induced obesity_Cers6<tm1Arte>/Cers6<tm1Arte>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0005659IC57BL6NFVBNCers6tm1ArteCers6tm1ArteTgAlb1cre7Gsc0TgAlb1cre7GscCers6tm1Arte
• decreased inflammatory response_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0001876IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• improved glucose tolerance_Cers6<tm1Arte>/Cers6<tm1Arte>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0005292IC57BL6NFVBNCers6tm1ArteCers6tm1ArteTgAlb1cre7Gsc0TgAlb1cre7GscCers6tm1Arte
• decreased total body fat amount_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0010025IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• improved glucose tolerance_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0005292IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• decreased circulating leptin level_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0005668IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• abnormal ceramide level_Cers6<tm1Arte>/Cers6<tm1Arte>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0012232IC57BL6NFVBNCers6tm1ArteCers6tm1ArteTgAlb1cre7Gsc0TgAlb1cre7GscCers6tm1Arte
• decreased brown fat cell lipid droplet size_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0009125IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• decreased susceptibility to diet-induced obesity_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0005659IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• decreased circulating insulin level_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0002727IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte
• increased fatty acid oxidation_Cers6<tm1.1Arte>/Cers6<tm1.1Arte>
  http://metadb.riken.jp/0014171IBALBcJC57BL6NCers6tm11ArteCers6tm11ArteCers6tm11Arte