Pawel M. Switonski, et.al., A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD., Neurobiology of disease, 2015, 73

http://rdf.ncbi.nlm.nih.gov/pubmed/25301414

Pawel M. Switonski, et.al., A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD., Neurobiology of disease, 2015, 73

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Atxn3<tm2.1(ATXN3*)Mfig>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5708157

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal Purkinje cell morphology_Atxn3<tm2.1(ATXN3*)Mfig>/Atxn3<+>
  http://metadb.riken.jp/0000877I129C57BL6JAtxn3tm21ATXN3MfigAtxn3Atxn3Atxn3tm21ATXN3Mfig
• astrocytosis_Atxn3<tm2.1(ATXN3*)Mfig>/Atxn3<+>
  http://metadb.riken.jp/0003354I129C57BL6JAtxn3tm21ATXN3MfigAtxn3Atxn3Atxn3tm21ATXN3Mfig
• impaired coordination_Atxn3<tm2.1(ATXN3*)Mfig>/Atxn3<+>
  http://metadb.riken.jp/0001405I129C57BL6JAtxn3tm21ATXN3MfigAtxn3Atxn3Atxn3tm21ATXN3Mfig
• neuronal cytoplasmic inclusions_Atxn3<tm2.1(ATXN3*)Mfig>/Atxn3<+>
  http://metadb.riken.jp/0011975I129C57BL6JAtxn3tm21ATXN3MfigAtxn3Atxn3Atxn3tm21ATXN3Mfig
• neurodegeneration_Atxn3<tm2.1(ATXN3*)Mfig>/Atxn3<+>
  http://metadb.riken.jp/0002229I129C57BL6JAtxn3tm21ATXN3MfigAtxn3Atxn3Atxn3tm21ATXN3Mfig
• neuronal intranuclear inclusions_Atxn3<tm2.1(ATXN3*)Mfig>/Atxn3<+>
  http://metadb.riken.jp/0004191I129C57BL6JAtxn3tm21ATXN3MfigAtxn3Atxn3Atxn3tm21ATXN3Mfig
• Purkinje cell degeneration_Atxn3<tm2.1(ATXN3*)Mfig>/Atxn3<+>
  http://metadb.riken.jp/0000876I129C57BL6JAtxn3tm21ATXN3MfigAtxn3Atxn3Atxn3tm21ATXN3Mfig

class

http://purl.org/net/cito/citesAsAuthority

• Atxn3<tm2.1(ATXN3*)Mfig>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5708157