Chandrashekhar R. Gandhi, et.al., Liver-specific deletion of augmenter of liver regeneration accelerates development of steatohepatitis and hepatocellular carcinoma in mice., Gastroenterology, 2015, 148

http://rdf.ncbi.nlm.nih.gov/pubmed/25448926

Chandrashekhar R. Gandhi, et.al., Liver-specific deletion of augmenter of liver regeneration accelerates development of steatohepatitis and hepatocellular carcinoma in mice., Gastroenterology, 2015, 148

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gfer<tm1.2Crg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5762605
• Gfer<tm1.1Crg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5762603

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating alanine transaminase level_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002941I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• hepatic necrosis_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001654I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• abnormal cellular respiration_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0010954I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• decreased liver cholesterol level_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0010026I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• abnormal endoplasmic reticulum morphology_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0009378I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• liver inflammation_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001860I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• abnormal liver morphology_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000598I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• increased hepatocellular carcinoma incidence_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003331I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• decreased body weight_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001262I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• decreased mitochondria number_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0011629I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• increased hepatocyte apoptosis_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003887I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• abnormal liver physiology_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000609I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• abnormal mitochondrial chromosome morphology_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>
  http://metadb.riken.jp/0011638I129C57BL6Gfertm11CrgGfertm11CrgGfertm11Crg
• abnormal mitochondrion morphology_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0006035I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• oxidative stress_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>
  http://metadb.riken.jp/0003674I129C57BL6Gfertm11CrgGfertm11CrgGfertm11Crg
• increased hepatocyte proliferation_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003893I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• increased liver triglyceride level_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0009355I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• abnormal oval cell physiology_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0010042I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• embryonic lethality, complete penetrance_Gfer<tm1.2Crg>/Gfer<tm1.2Crg>
  http://metadb.riken.jp/0011092I129C57BL6FVBNGfertm12CrgGfertm12CrgGfertm12Crg
• focal hepatic necrosis_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001656I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• dilated mitochondria_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0011632I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• increased liver weight_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002981I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• abnormal hepatocyte morphology_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>
  http://metadb.riken.jp/0000607I129C57BL6Gfertm11CrgGfertm11CrgGfertm11Crg
• abnormal mitochondrial crista morphology_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0011635I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• liver fibrosis_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003333I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• increased liver cholesterol level_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0010027I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• abnormal mitochondrial shape_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0011633I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• pale liver_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000603I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg
• hepatic steatosis_Gfer<tm1.1Crg>/Gfer<tm1.1Crg>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002628I129C57BL6DBAGfertm11CrgGfertm11CrgTgAlbcre21Mgn0TgAlbcre21MgnGfertm11Crg

class

http://purl.org/net/cito/citesAsAuthority

• Gfer<tm1.2Crg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5762605
• Gfer<tm1.1Crg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5762603