Diana M. Shih, et.al., PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/25477283

Diana M. Shih, et.al., PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, 29

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pon3<tm1Dmsh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5825222

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• oxidative stress_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0003674B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased retroperitoneal fat pad weight_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0009304B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• decreased liver triglyceride level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0009356B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased hepatocyte apoptosis_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0003887B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased bile salt level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0004789B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased circulating alanine transaminase level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0002941B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased subcutaneous adipose tissue amount_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0010934B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• abnormal protein level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0008469B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased liver cholesterol level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0010027B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• abnormal mitochondrial ATP synthesis coupled electron transport_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0010956B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• gallstones_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0002830B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• decreased circulating HDL cholesterol level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0000186B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased sensitivity to induced morbidity/mortality_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0009763B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• decreased oxygen consumption_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0005290B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased circulating bilirubin level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0005344B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased circulating triglyceride level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0001552B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• abnormal bile composition_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0004773B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• abnormal lipid level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0001547B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• decreased circulating free fatty acid level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0002702B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased circulating aspartate transaminase level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0005343B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased white fat cell lipid droplet size_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0009121B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased susceptibility to diet-induced obesity_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0005658B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• abnormal bile salt homeostasis_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0005365B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased circulating LDL cholesterol level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0000182B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased susceptibility to atherosclerosis_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0005339B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• decreased bile salt level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0012338B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased body weight_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0001260B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased circulating cholesterol level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0005178B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• decreased circulating triglyceride level_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0002644B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• liver inflammation_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0001860B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased gonadal fat pad weight_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0009285B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• jaundice_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0000611B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• increased white fat cell size_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0009118B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh
• decreased fatty acid oxidation_Pon3<tm1Dmsh>/Pon3<tm1Dmsh>
  http://metadb.riken.jp/0014172B6J129X1Pon3tm1DmshPon3tm1DmshPon3tm1DmshPon3tm1Dmsh

class

http://purl.org/net/cito/citesAsAuthority

• Pon3<tm1Dmsh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5825222