Jin. Zhang, et.al., Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors., Proceedings of the National Academy of Sciences of the United States of America, 2014, 111

http://rdf.ncbi.nlm.nih.gov/pubmed/25512531

Jin. Zhang, et.al., Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors., Proceedings of the National Academy of Sciences of the United States of America, 2014, 111

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53tm1TyjRbm38tm11XchTrp53tm1Tyj
• hepatic steatosis_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002628I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53Trp53Rbm38tm11XchTrp53tm1Tyj
• increased mortality induced by gamma-irradiation_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0001658IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• weight loss_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0001263IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• decreased gonadal fat pad weight_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0009283IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• premature death_Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6FVBNTrp53tm1TyjTrp53tm1TyjTrp53tm1Tyj
• anemia_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0001577IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• decreased tumor latency_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0010308I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53tm1TyjRbm38tm11XchTrp53tm1Tyj
• decreased hematocrit_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0000208IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• extramedullary hematopoiesis_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0000240IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• decreased tumor incidence_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002052I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53Trp53Rbm38tm11XchTrp53tm1Tyj
• abnormal spleen B cell follicle morphology_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0008470I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53Trp53Rbm38tm11XchTrp53tm1Tyj
• increased hemangiosarcoma incidence_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0003667IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• kyphosis_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0000160IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• altered tumor susceptibility_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002166I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53Trp53Rbm38tm11XchTrp53tm1Tyj
• increased megakaryocyte cell number_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0008254IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• decreased hemoglobin content_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0002874IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• premature death_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0002083IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• spontaneous skin ulceration_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0001209IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• premature death_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53Trp53Rbm38tm11XchTrp53tm1Tyj
• altered tumor susceptibility_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002166I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53tm1TyjRbm38tm11XchTrp53tm1Tyj
• increased lymphoma incidence_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0012431I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53tm1TyjRbm38tm11XchTrp53tm1Tyj
• decreased mortality induced by ionizing radiation_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003010I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53tm1TyjRbm38tm11XchTrp53tm1Tyj
• decreased tumor incidence_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002052I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53tm1TyjRbm38tm11XchTrp53tm1Tyj
• decreased mortality induced by ionizing radiation_Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003010I129S2SvPasC57BL6FVBNTrp53tm1TyjTrp53tm1TyjTrp53tm1Tyj
• increased lymphoma incidence_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0012431IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• abnormal erythrocyte morphology_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0002447IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• premature death_Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6FVBNTrp53tm1TyjTrp53Trp53tm1TyjTrp53
• decreased bone marrow cell number_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0000333IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• increased hepatoma incidence_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0010264IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• premature aging_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0003786IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• decreased total body fat amount_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0010025IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• increased spleen white pulp amount_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0008478IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• lordosis_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0000162IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• increased tumor incidence_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0002020IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• enlarged spleen_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>
  http://metadb.riken.jp/0000691IC57BL6FVBNRbm38tm11XchRbm38tm11XchRbm38tm11Xch
• decreased sarcoma incidence_Rbm38<tm1.1Xch>/Rbm38<tm1.1Xch>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0012415I129S2SvPasC57BL6FVBNRbm38tm11XchRbm38tm11XchTrp53tm1TyjTrp53tm1TyjRbm38tm11XchTrp53tm1Tyj