Meagan R. Pitcher, et.al., Rett syndrome like phenotypes in the R255X Mecp2 mutant mouse are rescued by MECP2 transgene., Human molecular genetics, 2015, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/25634563

Meagan R. Pitcher, et.al., Rett syndrome like phenotypes in the R255X Mecp2 mutant mouse are rescued by MECP2 transgene., Human molecular genetics, 2015, 24

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf
• impaired contextual conditioning behavior_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0009454I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf
• reduced long term potentiation_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0001473I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf
• increased liver weight_Mecp2<tm1.1Irsf>/Mecp2<+>
  http://metadb.riken.jp/0002981I129S2SvPasC57BL6Mecp2tm11IrsfMecp2Mecp2Mecp2tm11Irsf
• decreased brain weight_Mecp2<tm1.1Irsf>/Mecp2<+>
  http://metadb.riken.jp/0002175I129S2SvPasC57BL6Mecp2tm11IrsfMecp2Mecp2Mecp2tm11Irsf
• decreased brain weight_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0002175I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf
• premature death_Mecp2<tm1.1Irsf>/Mecp2<+>
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6Mecp2tm11IrsfMecp2Mecp2Mecp2tm11Irsf
• irregular heartbeat_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0001636I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf
• decreased body weight_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0001262I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf
• decreased anxiety-related response_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0001364I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf
• prolonged QT interval_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0003233I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf
• increased heart weight_Mecp2<tm1.1Irsf>/Mecp2<+>
  http://metadb.riken.jp/0002833I129S2SvPasC57BL6Mecp2tm11IrsfMecp2Mecp2Mecp2tm11Irsf
• impaired coordination_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0001405I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf
• tonic-clonic seizures_Mecp2<tm1.1Irsf>/Mecp2<+>
  http://metadb.riken.jp/0003997I129S2SvPasC57BL6Mecp2tm11IrsfMecp2Mecp2Mecp2tm11Irsf
• abnormal excitatory postsynaptic potential_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0002912I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf
• impaired coordination_Mecp2<tm1.1Irsf>/Mecp2<+>
  http://metadb.riken.jp/0001405I129S2SvPasC57BL6Mecp2tm11IrsfMecp2Mecp2Mecp2tm11Irsf
• prolonged QT interval_Mecp2<tm1.1Irsf>/Mecp2<+>
  http://metadb.riken.jp/0003233I129S2SvPasC57BL6Mecp2tm11IrsfMecp2Mecp2Mecp2tm11Irsf
• increased body weight_Mecp2<tm1.1Irsf>/Mecp2<+>
  http://metadb.riken.jp/0001260I129S2SvPasC57BL6Mecp2tm11IrsfMecp2Mecp2Mecp2tm11Irsf
• increased pulmonary respiratory rate_Mecp2<tm1.1Irsf>/Mecp2<+>
  http://metadb.riken.jp/0005573I129S2SvPasC57BL6Mecp2tm11IrsfMecp2Mecp2Mecp2tm11Irsf
• increased pulmonary respiratory rate_Mecp2<tm1.1Irsf>/Y
  http://metadb.riken.jp/0005573I129S2SvPasC57BL6Mecp2tm11IrsfYMecp2tm11Irsf