Shao H. Yang, et.al., Mice that express farnesylated versions of prelamin A in neurons develop achalasia., Human molecular genetics, 2015, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/25652409

Shao H. Yang, et.al., Mice that express farnesylated versions of prelamin A in neurons develop achalasia., Human molecular genetics, 2015, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lmna<tm11Lgf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5752218

class

http://purl.org/net/cito/citesAsAuthority

• Lmna<tm11Lgf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5752218

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal esophageal smooth muscle morphology_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0003159I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• premature death_Lmna<tm11Lgf>/Lmna<tm11Lgf>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Lmnatm11LgfLmnatm11LgfLmnatm11Lgf
• abnormal enteric neuron morphology_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0001046I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• weight loss_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0001263I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• abnormal interstitial cell of Cajal morphology_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0009536I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• abnormal colon morphology_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0000495I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• dilated esophagus_Lmna<tm10Lgf>/Lmna<tm10Lgf>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0004548I129P2OlaHsd129S4SvJaeLmnatm10LgfLmnatm10LgfZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1SgyLmnatm10Lgf
• distended cecum_Lmna<tm10Lgf>/Lmna<tm10Lgf>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0009480I129P2OlaHsd129S4SvJaeLmnatm10LgfLmnatm10LgfZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1SgyLmnatm10Lgf
• abnormal esophageal squamous epithelium morphology_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0000469I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• distended cecum_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0009480I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• esophageal achalasia_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0011570I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• abnormal cholinergic neuron morphology_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0001038I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• abnormal colon morphology_Lmna<tm10Lgf>/Lmna<tm10Lgf>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0000495I129P2OlaHsd129S4SvJaeLmnatm10LgfLmnatm10LgfZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1SgyLmnatm10Lgf
• abnormal esophageal squamous epithelium morphology_Lmna<tm10Lgf>/Lmna<tm10Lgf>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0000469I129P2OlaHsd129S4SvJaeLmnatm10LgfLmnatm10LgfZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1SgyLmnatm10Lgf
• decreased body size_Lmna<tm11Lgf>/Lmna<tm11Lgf>
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6Lmnatm11LgfLmnatm11LgfLmnatm11Lgf
• premature death_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• dilated esophagus_Lmna<tm11Lgf>/Lmna<+>
  http://metadb.riken.jp/0004548I129P2OlaHsdC57BL6Lmnatm11LgfLmnaLmnaLmnatm11Lgf
• esophageal achalasia_Lmna<tm10Lgf>/Lmna<tm10Lgf>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0011570I129P2OlaHsd129S4SvJaeLmnatm10LgfLmnatm10LgfZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1SgyLmnatm10Lgf