Yong Kyung. Kim, et.al., Disruption of CR6-interacting factor-1 (CRIF1) in mouse islet beta cells leads to mitochondrial diabetes with progressive beta cell failure., Diabetologia, 2015, 58

http://rdf.ncbi.nlm.nih.gov/pubmed/25660120

Yong Kyung. Kim, et.al., Disruption of CR6-interacting factor-1 (CRIF1) in mouse islet beta cells leads to mitochondrial diabetes with progressive beta cell failure., Diabetologia, 2015, 58

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased insulin secretion_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003059I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• decreased pancreatic beta cell number_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003339I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• abnormal pancreatic beta cell physiology_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003562I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• abnormal pancreatic islet morphology_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005215I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• abnormal pancreatic beta cell morphology_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005217I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• decreased oxygen consumption_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005290I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
他8件を見る
• impaired glucose tolerance_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• abnormal mitochondrion morphology_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0006035I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• abnormal mitochondrial physiology_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0006036I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• decreased pancreatic beta cell mass_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009114I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• increased mitochondria number_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0011628I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• abnormal mitochondrial crista morphology_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0011635I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• abnormal mitochondrial matrix morphology_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0011637I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn
• decreased pancreatic beta cell proliferation_Gadd45gip1<tm2Kong>/Gadd45gip1<tm2Kong>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0011820I129P2OlaHsdC57BL6DBAGadd45gip1tm2KongGadd45gip1tm2KongTgIns2cre25Mgn0Gadd45gip1tm2KongTgIns2cre25Mgn