Bernhard Clemens. Richard, et.al., Gene Dosage Dependent Aggravation of the Neurological Phenotype in the 5XFAD Mouse Model of Alzheimer's Disease., Journal of Alzheimer's disease : JAD, 2015, 45

http://rdf.ncbi.nlm.nih.gov/pubmed/25697701

Bernhard Clemens. Richard, et.al., Gene Dosage Dependent Aggravation of the Neurological Phenotype in the 5XFAD Mouse Model of Alzheimer's Disease., Journal of Alzheimer's disease : JAD, 2015, 45

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body weight_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0
  http://metadb.riken.jp/0001262B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgAPPSwFlLonPSEN1M146LL286V6799Vas
• impaired coordination_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0001405B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• axonal spheroids_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0010047B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• amyloid beta deposits_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0003329B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• decreased litter size_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0001935B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• decreased anxiety-related response_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0001364B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• impaired spatial learning_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0012307B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• cachexia_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0005150B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• impaired balance_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0001525B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• decreased body weight_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0001262B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• impaired swimming_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0001522B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• abnormal spatial reference memory_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0008414B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• paresis_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0000754B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• decreased anxiety-related response_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0
  http://metadb.riken.jp/0001364B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgAPPSwFlLonPSEN1M146LL286V6799Vas
• limb grasping_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0
  http://metadb.riken.jp/0001513B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgAPPSwFlLonPSEN1M146LL286V6799Vas
• abnormal posture_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0001504B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• pup cannibalization_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0001385B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas
• limb grasping_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
  http://metadb.riken.jp/0001513B6CgTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799VasTgAPPSwFlLonPSEN1M146LL286V6799Vas