Rim. Rzem, et.al., A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair., PloS one, 2015, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/25763823

Rim. Rzem, et.al., A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair., PloS one, 2015, 10

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased vertical activity_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0002574I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• hyperactivity_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0001399I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• abnormal amino acid level_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0005332I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• abnormal oligodendrocyte morphology_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0000953I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• abnormal glial cell morphology_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0003634I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• abnormal spatial working memory_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0008428I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• abnormal brain morphology_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0002152I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• impaired spatial learning_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0012307I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• fatigue_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0002899I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• abnormal habituation_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0011617I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• abnormal myelin sheath morphology_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0003871I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi
• increased susceptibility to pharmacologically induced seizures_L2hgdh<Gt(DC0625)Wtsi>/L2hgdh<Gt(DC0625)Wtsi>
  http://metadb.riken.jp/0002906I129P2OlaHsdC57BL6L2hgdhGtDC0625WtsiL2hgdhGtDC0625WtsiL2hgdhGtDC0625Wtsi