Anna. Iervolino, et.al., Selective dicer suppression in the kidney alters GSK3β/β-catenin pathways promoting a glomerulocystic disease., PloS one, 2015, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/25799508

Anna. Iervolino, et.al., Selective dicer suppression in the kidney alters GSK3β/β-catenin pathways promoting a glomerulocystic disease., PloS one, 2015, 10

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased kidney collecting duct number_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0011846I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• abnormal renal tubule epithelial cell primary cilium morphology_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0011066I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• dilated renal tubules_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0002705I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• increased urine protein level_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0002962I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• renal interstitial fibrosis_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0003215I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• albuminuria_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0002871I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• increased kidney cell proliferation_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0011440I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• isosthenuria_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0013305I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• pale kidney_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0004969I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• dilated renal glomerular capsule_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0003670I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• abnormal renal glomerulus morphology_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0005325I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• increased fluid intake_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0011941I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• kidney cortex cysts_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0000522I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• abnormal renal corpuscle morphology_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0002827I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• increased kidney apoptosis_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0011368I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• decreased renal glomerular filtration rate_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0005528I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• decreased urine osmolality_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0002988I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• abnormal kidney morphology_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0002135I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• decreased body weight_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0001262I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• polyuria_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0001762I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8
• decreased kidney weight_Dicer1<tm1Smr>/Dicer1<tm1Smr>,Pax8<tm1.1(cre)Mbu>/Pax8<+>
  http://metadb.riken.jp/0003918I129P2OlaHsd129S7SvEvBrdDicer1tm1SmrDicer1tm1SmrPax8tm11creMbuPax8Dicer1tm1SmrPax8tm11creMbuPax8