Edward. Rockenstein, et.al., A novel triple repeat mutant tau transgenic model that mimics aspects of pick's disease and fronto-temporal tauopathies., PloS one, 2015, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/25803611

Edward. Rockenstein, et.al., A novel triple repeat mutant tau transgenic model that mimics aspects of pick's disease and fronto-temporal tauopathies., PloS one, 2015, 10

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-MAPT*L266V*G272V)13Ema
  http://metadb.riken.jp/db/mgi_rdf/MGI:5774860

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-MAPT*L266V*G272V)13Ema
  http://metadb.riken.jp/db/mgi_rdf/MGI:5774860

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal dentate gyrus morphology_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0000812IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• decreased neuron number_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0008948IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• tau protein deposits_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0004250IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• hyperactivity_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0001399IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• abnormal dendrite morphology_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0008143IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• increased vertical activity_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0002574IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• impaired spatial learning_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0012307IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• decreased neocortex volume_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0020070IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• increased thigmotaxis_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0002797IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• axonal dystrophy_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0003225IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• neuronal intranuclear inclusions_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0004191IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• neurodegeneration_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0002229IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• abnormal spatial reference memory_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0008414IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• abnormal habituation to a new environment_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0011620IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema
• impaired coordination_Tg(Thy1-MAPT*L266V*G272V)13Ema/0
  http://metadb.riken.jp/0001405IC57BL6DBA2TgThy1MAPTL266VG272V13Ema0TgThy1MAPTL266VG272V13Ema