Liang. Ye, et.al., Osteopetrorickets due to Snx10 deficiency in mice results from both failed osteoclast activity and loss of gastric acid-dependent calcium absorption., PLoS genetics, 2015, 11

http://rdf.ncbi.nlm.nih.gov/pubmed/25811986

Liang. Ye, et.al., Osteopetrorickets due to Snx10 deficiency in mice results from both failed osteoclast activity and loss of gastric acid-dependent calcium absorption., PLoS genetics, 2015, 11

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Snx10<tm1c(EUCOMM)Raba>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5690197
• Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5690193

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal bone mineralization_Tcirg1<tm1Ypl>/Tcirg1<tm1Ypl>
  http://metadb.riken.jp/0002896I129S4SvJaeC57BL6JTcirg1tm1YplTcirg1tm1YplTcirg1tm1Ypl
• abnormal gastric parietal cell morphology_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0004139I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• osteopetrosis_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0000067I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• osteomalacia_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0009445I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• decreased bone volume_Ctsk<tm1(cre)Ska>/Ctsk<+>,Snx10<tm1c(EUCOMM)Raba>/Snx10<tm1c(EUCOMM)Raba>
  http://metadb.riken.jp/0010876I129S4SvJaeC57BL6C57BL6JC57BL6NCrljCBAJNCrljCtsktm1creSkaCtskSnx10tm1cEUCOMMRabaSnx10tm1cEUCOMMRabaCtsktm1creSkaSnx10tm1cEUCOMMRabaCtsk
• failure of tooth eruption_Ctsk<tm1(cre)Ska>/Ctsk<+>,Snx10<tm1c(EUCOMM)Raba>/Snx10<tm1c(EUCOMM)Raba>
  http://metadb.riken.jp/0000121I129S4SvJaeC57BL6C57BL6JC57BL6NCrljCBAJNCrljCtsktm1creSkaCtskSnx10tm1cEUCOMMRabaSnx10tm1cEUCOMMRabaCtsktm1creSkaSnx10tm1cEUCOMMRabaCtsk
• postnatal growth retardation_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0001732I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• increased circulating parathyroid hormone level_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0002904I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• increased bone volume_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0010875I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• rickets_Tcirg1<tm1Ypl>/Tcirg1<tm1Ypl>
  http://metadb.riken.jp/0003116I129S4SvJaeC57BL6JTcirg1tm1YplTcirg1tm1YplTcirg1tm1Ypl
• decreased bone mineral content_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0010124I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• decreased bone trabecular spacing_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0013631I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• rickets_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0003116I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• premature death_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• abnormal stomach morphology_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0000470I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• osteopetrosis_Ctsk<tm1(cre)Ska>/Ctsk<+>,Snx10<tm1c(EUCOMM)Raba>/Snx10<tm1c(EUCOMM)Raba>
  http://metadb.riken.jp/0000067I129S4SvJaeC57BL6C57BL6JC57BL6NCrljCBAJNCrljCtsktm1creSkaCtskSnx10tm1cEUCOMMRabaSnx10tm1cEUCOMMRabaCtsktm1creSkaSnx10tm1cEUCOMMRabaCtsk
• failure of tooth eruption_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0000121I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• decreased compact bone thickness_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0000135I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• abnormal epiphyseal plate morphology_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0006395I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• decreased vitamin D level_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0012336I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• decreased bone stiffness_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0013639I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• postnatal growth retardation_Ctsk<tm1(cre)Ska>/Ctsk<+>,Snx10<tm1c(EUCOMM)Raba>/Snx10<tm1c(EUCOMM)Raba>
  http://metadb.riken.jp/0001732I129S4SvJaeC57BL6C57BL6JC57BL6NCrljCBAJNCrljCtsktm1creSkaCtskSnx10tm1cEUCOMMRabaSnx10tm1cEUCOMMRabaCtsktm1creSkaSnx10tm1cEUCOMMRabaCtsk
• increased stomach pH_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0008006I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• decreased bone mineral density_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0000063I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• decreased bone strength_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0004991I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• increased bone mineral density_Ctsk<tm1(cre)Ska>/Ctsk<+>,Snx10<tm1c(EUCOMM)Raba>/Snx10<tm1c(EUCOMM)Raba>
  http://metadb.riken.jp/0000062I129S4SvJaeC57BL6C57BL6JC57BL6NCrljCBAJNCrljCtsktm1creSkaCtskSnx10tm1cEUCOMMRabaSnx10tm1cEUCOMMRabaCtsktm1creSkaSnx10tm1cEUCOMMRabaCtsk
• abnormal osteoclast physiology_Ctsk<tm1(cre)Ska>/Ctsk<+>,Snx10<tm1c(EUCOMM)Raba>/Snx10<tm1c(EUCOMM)Raba>
  http://metadb.riken.jp/0001541I129S4SvJaeC57BL6C57BL6JC57BL6NCrljCBAJNCrljCtsktm1creSkaCtskSnx10tm1cEUCOMMRabaSnx10tm1cEUCOMMRabaCtsktm1creSkaSnx10tm1cEUCOMMRabaCtsk
• abnormal bone structure_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0003795I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• absent compact bone_Tcirg1<tm1Ypl>/Tcirg1<tm1Ypl>
  http://metadb.riken.jp/0010969I129S4SvJaeC57BL6JTcirg1tm1YplTcirg1tm1YplTcirg1tm1Ypl
• abnormal gastric chief cell morphology_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0004140I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• decreased circulating calcium level_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0000195I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• abnormal skeleton development_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0002113I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• increased osteoid volume_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0010926I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• abnormal epiphyseal plate morphology_Ctsk<tm1(cre)Ska>/Ctsk<+>,Snx10<tm1c(EUCOMM)Raba>/Snx10<tm1c(EUCOMM)Raba>
  http://metadb.riken.jp/0006395I129S4SvJaeC57BL6C57BL6JC57BL6NCrljCBAJNCrljCtsktm1creSkaCtskSnx10tm1cEUCOMMRabaSnx10tm1cEUCOMMRabaCtsktm1creSkaSnx10tm1cEUCOMMRabaCtsk
• abnormal long bone metaphysis morphology_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0000133I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• decreased vitamin D level_Tcirg1<tm1Ypl>/Tcirg1<tm1Ypl>
  http://metadb.riken.jp/0012336I129S4SvJaeC57BL6JTcirg1tm1YplTcirg1tm1YplTcirg1tm1Ypl
• abnormal osteoclast physiology_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0001541I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• decreased circulating calcium level_Tcirg1<tm1Ypl>/Tcirg1<tm1Ypl>
  http://metadb.riken.jp/0000195I129S4SvJaeC57BL6JTcirg1tm1YplTcirg1tm1YplTcirg1tm1Ypl
• increased bone trabecula number_Snx10<tm1a(EUCOMM)Raba>/Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/0010868I129S4SvJaeC57BL6C57BL6JSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRabaSnx10tm1aEUCOMMRaba
• osteopetrosis_Tcirg1<tm1Ypl>/Tcirg1<tm1Ypl>
  http://metadb.riken.jp/0000067I129S4SvJaeC57BL6JTcirg1tm1YplTcirg1tm1YplTcirg1tm1Ypl
• abnormal long bone metaphysis morphology_Tcirg1<tm1Ypl>/Tcirg1<tm1Ypl>
  http://metadb.riken.jp/0000133I129S4SvJaeC57BL6JTcirg1tm1YplTcirg1tm1YplTcirg1tm1Ypl

class

http://purl.org/net/cito/citesAsAuthority

• Snx10<tm1c(EUCOMM)Raba>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5690197
• Snx10<tm1a(EUCOMM)Raba>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5690193