Marion. Seillier, et.al., Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1., EMBO molecular medicine, 2015, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/25828351

Marion. Seillier, et.al., Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1., EMBO molecular medicine, 2015, 7

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• insulin resistance_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0005331I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• increased susceptibility to diet-induced obesity_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0005658I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• abnormal mitochondrial physiology_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0006036I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• oxidative stress_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0003674I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• abnormal epididymal fat pad morphology_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0006319I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• hepatic steatosis_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0002628I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• increased susceptibility to diet-induced non-insulin dependent diabetes_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0020089I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• abnormal oxidative phosphorylation_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0010959I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• abnormal cell morphology_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0000358I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• increased mitochondria number_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0011628I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• abnormal respiratory electron transport chain_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0010955I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• abnormal mitochondrion morphology_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0006035I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• abnormal mitophagy_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0014046I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• increased body weight_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0001260I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• abnormal renal fat pad morphology_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0008902I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• increased liver weight_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0002981I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• increased circulating insulin level_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0002079I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• increased body fat mass_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0014142I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• impaired glucose tolerance_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0005293I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar
• hyperglycemia_Trp53inp1<tm1Acar>/Trp53inp1<tm1Acar>
  http://metadb.riken.jp/0001559I129SvC57BL6Trp53inp1tm1AcarTrp53inp1tm1AcarTrp53inp1tm1Acar