Yongfeng. Gong, et.al., KLHL3 regulates paracellular chloride transport in the kidney by ubiquitination of claudin-8., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112

http://rdf.ncbi.nlm.nih.gov/pubmed/25831548

Yongfeng. Gong, et.al., KLHL3 regulates paracellular chloride transport in the kidney by ubiquitination of claudin-8., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cldn8<tm1.1Jhou>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5750892

class

http://purl.org/net/cito/citesAsAuthority

• Cldn8<tm1.1Jhou>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5750892

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal kidney collecting duct morphology_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0004754B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• decreased mean systemic arterial blood pressure_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0004876B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• hypokalemia_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0004119B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• decreased circulating chloride level_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0003020B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• increased urine sodium level_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0006316B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• alkalosis_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0003028B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• hypotension_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0001596B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• increased circulating aldosterone level_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0002666B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• increased urine potassium level_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0005619B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• decreased circulating potassium level_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0005628B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• polyuria_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0001762B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• increased circulating bicarbonate level_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0003016B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek
• increased urine chloride ion level_Cldn8<tm1.1Jhou>/Cldn8<tm1.1Jhou>,Tg(Aqp2-cre)1Dek/0
  http://metadb.riken.jp/0011459B6CgCldn8tm11JhouTgAqp2cre1DekCldn8tm11JhouCldn8tm11JhouTgAqp2cre1Dek0Cldn8tm11JhouTgAqp2cre1Dek