M. Yue, et.al., Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice., Neurobiology of disease, 2015, 78

http://rdf.ncbi.nlm.nih.gov/pubmed/25836420

M. Yue, et.al., Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice., Neurobiology of disease, 2015, 78

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5750894

class

http://purl.org/net/cito/citesAsAuthority

• Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5750894

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal locomotor behavior_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0001392IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• hyperactivity_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0001399IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• abnormal motor coordination/ balance_Lrrk2<tm1.1Hlme>/Lrrk2<+>
  http://metadb.riken.jp/0001516IC57BL6C57BL6JLrrk2tm11HlmeLrrk2Lrrk2Lrrk2tm11Hlme
• abnormal lipid level_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0001547IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• abnormal dopamine level_Lrrk2<tm1.1Hlme>/Lrrk2<+>
  http://metadb.riken.jp/0001905IC57BL6C57BL6JLrrk2tm11HlmeLrrk2Lrrk2Lrrk2tm11Hlme
• abnormal dopamine level_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0001905IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
他14件を見る
• enhanced coordination_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0003858IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• tau protein deposits_Lrrk2<tm1.1Hlme>/Lrrk2<+>
  http://metadb.riken.jp/0004250IC57BL6C57BL6JLrrk2tm11HlmeLrrk2Lrrk2Lrrk2tm11Hlme
• tau protein deposits_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0004250IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• abnormal mitochondrion morphology_Lrrk2<tm1.1Hlme>/Lrrk2<+>
  http://metadb.riken.jp/0006035IC57BL6C57BL6JLrrk2tm11HlmeLrrk2Lrrk2Lrrk2tm11Hlme
• abnormal mitochondrion morphology_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0006035IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• abnormal mitochondrial fission_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0006037IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• abnormal synaptic dopamine release_Lrrk2<tm1.1Hlme>/Lrrk2<+>
  http://metadb.riken.jp/0010149IC57BL6C57BL6JLrrk2tm11HlmeLrrk2Lrrk2Lrrk2tm11Hlme
• abnormal synaptic dopamine release_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0010149IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• decreased mitochondria number_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0011629IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• dilated mitochondria_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0011632IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• abnormal mitochondrial shape_Lrrk2<tm1.1Hlme>/Lrrk2<+>
  http://metadb.riken.jp/0011633IC57BL6C57BL6JLrrk2tm11HlmeLrrk2Lrrk2Lrrk2tm11Hlme
• abnormal mitochondrial shape_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0011633IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme
• abnormal mitochondrial crista morphology_Lrrk2<tm1.1Hlme>/Lrrk2<+>
  http://metadb.riken.jp/0011635IC57BL6C57BL6JLrrk2tm11HlmeLrrk2Lrrk2Lrrk2tm11Hlme
• abnormal mitochondrial crista morphology_Lrrk2<tm1.1Hlme>/Lrrk2<tm1.1Hlme>
  http://metadb.riken.jp/0011635IC57BL6C57BL6JLrrk2tm11HlmeLrrk2tm11HlmeLrrk2tm11Hlme