Lindsay A. Bonsignore, et.al., NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging., Mechanisms of ageing and development, 2015, 146-148

http://rdf.ncbi.nlm.nih.gov/pubmed/25843235

Lindsay A. Bonsignore, et.al., NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging., Mechanisms of ageing and development, 2015, 146-148

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• female infertility_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0001926IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• preweaning lethality, incomplete penetrance_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0011110IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• increased cellular sensitivity to oxidative stress_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0008412IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• absent corpus luteum_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0001134IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• skin fibrosis_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0009932IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• decreased body weight_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0001262IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• abnormal mitochondrial physiology_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0006036IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• premature hair loss_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0005114IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• decreased body size_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0001265IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• abnormal liver morphology_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0000598IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• premature aging_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0003786IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• kyphosis_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0000160IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• premature death_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0002083IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• small ovary_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0001127IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• liver degeneration_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0003103IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• anovulation_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0008869IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• oxidative stress_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0003674IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• thin epidermis_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0001218IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• abnormal blood vessel morphology_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0001614IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc
• ovary cysts_Ntmt1<tm1(NCOM)Mfgc>/Ntmt1<tm1(NCOM)Mfgc>
  http://metadb.riken.jp/0002016IC57BL6JC57BL6NCrlNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgcNtmt1tm1NCOMMfgc