Hanqian. Mao, et.al., Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, 35

http://rdf.ncbi.nlm.nih.gov/pubmed/25948253

Hanqian. Mao, et.al., Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, 35

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rbm8a<tm1Dlsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5644432

class

http://purl.org/net/cito/citesAsAuthority

• Rbm8a<tm1Dlsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5644432

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased neuron number_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0008947IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• impaired neuron differentiation_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0011827IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• abnormal telencephalon development_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0000934IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• increased forebrain apoptosis_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0012504IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• small brain ventricles_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0013227IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• premature neuronal precursor differentiation_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0003424IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• increased neuronal precursor proliferation_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0020393IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• abnormal stratification in cerebral cortex_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0000790IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• decreased neocortex size_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0020069IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• decreased brain size_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0000774IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• ectopic cortical neuron_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0011724IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• abnormal cerebral cortex morphology_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0000788IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• thin cerebral cortex_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0006254IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• abnormal radial glial cell morphology_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0003648IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• increased neuron apoptosis_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0003203IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• microcephaly_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0000433IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• abnormal radial glial cell apoptosis_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0020392IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• decreased neuronal precursor cell number_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0004981IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a
• decreased radial glial cell number_Emx1<tm1(cre)Krj>/Emx1<+>,Rbm8a<tm1Dlsi>/Rbm8a<+>
  http://metadb.riken.jp/0020388IC57BL6JEmx1tm1creKrjEmx1Rbm8atm1DlsiRbm8aRbm8atm1DlsiEmx1tm1creKrjEmx1Rbm8a