M. Zhang, et.al., RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis., Cell death and differentiation, 2015, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/25952549

M. Zhang, et.al., RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis., Cell death and differentiation, 2015, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ufl1<tm1c(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5825300

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased erythroid progenitor cell number_Ufl1<tm1a(EUCOMM)Wtsi>/Ufl1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008973IC57BL6NUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsi
• decreased erythroid progenitor cell number_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008973I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• decreased monocyte cell number_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000223I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• decreased embryo size_Ufl1<tm1a(EUCOMM)Wtsi>/Ufl1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001698IC57BL6NUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsi
• decreased hemoglobin content_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002874I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• pancytopenia_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005152I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• increased nucleated erythrocyte cell number_Ufl1<tm1a(EUCOMM)Wtsi>/Ufl1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009395IC57BL6NUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsi
• small liver_Ufl1<tm1a(EUCOMM)Wtsi>/Ufl1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000601IC57BL6NUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsi
• weight loss_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001263I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• thrombocytopenia_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003179I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• abnormal bone marrow cell physiology_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0009278I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• decreased granulocyte number_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000334I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• decreased erythrocyte cell number_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002875I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• decreased hematocrit_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000208I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• abnormal autophagy_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008260I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• premature death_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002083I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• anemia_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001577I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• decreased leukocyte cell number_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000221I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor
• embryonic lethality during organogenesis, complete penetrance_Ufl1<tm1a(EUCOMM)Wtsi>/Ufl1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0011098IC57BL6NUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsi
• anemia_Ufl1<tm1a(EUCOMM)Wtsi>/Ufl1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001577IC57BL6NUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsiUfl1tm1aEUCOMMWtsi
• decreased lymphocyte cell number_Ufl1<tm1c(EUCOMM)Wtsi>/Ufl1<tm1c(EUCOMM)Wtsi>,Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005016I129S4SvJaeC3HC57BL6C57BL6NUfl1tm1cEUCOMMWtsiUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26SorUfl1tm1cEUCOMMWtsiGtROSA26Sortm1creERT2TyjGtROSA26Sor

class

http://purl.org/net/cito/citesAsAuthority

• Ufl1<tm1c(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5825300