Kerry M. Dorr, et.al., Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development., Development (Cambridge, England), 2015, 142

http://rdf.ncbi.nlm.nih.gov/pubmed/25953344

Kerry M. Dorr, et.al., Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development., Development (Cambridge, England), 2015, 142

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Casz1<tm1.1Flc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5638931
• Casz1<tm2(cre/ERT2)Flc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5638932

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart development_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000267I129P2OlaHsdC57BL6C57BL6JCBASJLCasz1tm11FlcCasz1tm11FlcTgSox2cre1Amc0TgSox2cre1AmcCasz1tm11Flc
• edema_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0001785I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• trabecula carnea hypoplasia_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0000295I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• hemorrhage_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0001914I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• decreased mitotic index_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0004759I129P2OlaHsd129X1SvJC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcIsl1tm1creTmjIsl1Isl1tm1creTmjCasz1tm11FlcIsl1
• lethality throughout fetal growth and development, complete penetrance_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0011099I129P2OlaHsd129X1SvJC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcIsl1tm1creTmjIsl1Isl1tm1creTmjCasz1tm11FlcIsl1
• abnormal heart shape_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0000277I129P2OlaHsd129X1SvJC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcIsl1tm1creTmjIsl1Isl1tm1creTmjCasz1tm11FlcIsl1
• abnormal fetal cardiomyocyte morphology_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0008788I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• abnormal cell cycle checkpoint function_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0004045I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• abnormal interventricular septum morphology_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0000281I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• decreased mitotic index_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0004759I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• embryonic lethality during organogenesis, complete penetrance_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6C57BL6JCBASJLCasz1tm11FlcCasz1tm11FlcTgSox2cre1Amc0TgSox2cre1AmcCasz1tm11Flc
• abnormal fetal cardiomyocyte physiology_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0011390I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• abnormal heart ventricle morphology_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0005294I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• enlarged heart right atrium_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0008727I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• poor circulation_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0001633I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• thin ventricular wall_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0000280I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• heart hypoplasia_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0002740I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• heart hypoplasia_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002740I129P2OlaHsdC57BL6C57BL6JCBASJLCasz1tm11FlcCasz1tm11FlcTgSox2cre1Amc0TgSox2cre1AmcCasz1tm11Flc
• perimembraneous ventricular septal defect_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0010418I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• embryonic lethality during organogenesis, complete penetrance_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0011098I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• abnormal heart development_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0000267I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• abnormal heart right ventricle morphology_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0003920I129P2OlaHsd129X1SvJC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcIsl1tm1creTmjIsl1Isl1tm1creTmjCasz1tm11FlcIsl1
• abnormal heart left ventricle morphology_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0003921I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• decreased fetal cardiomyocyte proliferation_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0011395I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• dilated heart right atrium_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0004062I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• abnormal heart apex morphology_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0012515I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• ventricular septal defect_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0010402I129P2OlaHsdC57BL6C57BL6JCBASJLCasz1tm11FlcCasz1tm11FlcTgSox2cre1Amc0TgSox2cre1AmcCasz1tm11Flc
• thin myocardium_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0002652I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• distended pericardium_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0000292I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• thin ventricular wall_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000280I129P2OlaHsdC57BL6C57BL6JCBASJLCasz1tm11FlcCasz1tm11FlcTgSox2cre1Amc0TgSox2cre1AmcCasz1tm11Flc
• abnormal heart shape_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0000277I129P2OlaHsd129S7SvEvBrdC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcNkx25tm1creRjsNkx25Casz1tm11FlcNkx25tm1creRjsNkx25
• heart right ventricle hypoplasia_Casz1<tm1.1Flc>/Casz1<tm1.1Flc>,Isl1<tm1(cre)Tmj>/Isl1<+>
  http://metadb.riken.jp/0010422I129P2OlaHsd129X1SvJC57BL6C57BL6JSJLCasz1tm11FlcCasz1tm11FlcIsl1tm1creTmjIsl1Isl1tm1creTmjCasz1tm11FlcIsl1

class

http://purl.org/net/cito/citesAsAuthority

• Casz1<tm1.1Flc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5638931
• Casz1<tm2(cre/ERT2)Flc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5638932