Eunhee. Kim, et.al., SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition., Cancer cell, 2015, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/25965569

Eunhee. Kim, et.al., SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition., Cancer cell, 2015, 27

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Srsf2<tm1.1Oaw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5694699

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• failure of myelopoiesis_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0001603B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• abnormal cell cycle_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0003077B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• impaired hematopoiesis_Srsf2<tm1Xdfu>/Srsf2<tm1Xdfu>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0001606I129S4SvJaeC57BL6JCBAJSrsf2tm1XdfuSrsf2tm1XdfuTgMx1cre1CgnTgMx1cre1CgnSrsf2tm1Xdfu
• bone marrow failure_Srsf2<tm1Xdfu>/Srsf2<tm1Xdfu>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0013776I129S4SvJaeC57BL6JCBAJSrsf2tm1XdfuSrsf2tm1XdfuTgMx1cre1CgnTgMx1cre1CgnSrsf2tm1Xdfu
• abnormal hematopoietic system physiology_Srsf2<tm1Xdfu>/Srsf2<tm1Xdfu>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0001545I129S4SvJaeC57BL6JCBAJSrsf2tm1XdfuSrsf2tm1XdfuTgMx1cre1CgnTgMx1cre1CgnSrsf2tm1Xdfu
• abnormal erythropoiesis_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0000245B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• abnormal erythroid progenitor cell morphology_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0008801B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• abnormal myelopoiesis_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0001601B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• impaired hematopoiesis_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0001606B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• increased apoptosis_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0006042B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• abnormal hematopoietic system physiology_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0001545B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• abnormal neutrophil morphology_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0005065B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• macrocytic anemia_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0002811B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• decreased B cell number_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0005017B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• increased hematopoietic stem cell number_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0004809B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2
• abnormal hematopoietic stem cell physiology_Srsf2<tm1.1Oaw>/Srsf2<+>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0010763B6CgTgMx1cre1CgnSrsf2tm11OawSrsf2tm11OawSrsf2TgMx1cre1CgnTgMx1cre1CgnSrsf2tm11OawSrsf2

class

http://purl.org/net/cito/citesAsAuthority

• Srsf2<tm1.1Oaw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5694699