Junqiang. Ye, et.al., hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112

http://rdf.ncbi.nlm.nih.gov/pubmed/26039991

Junqiang. Ye, et.al., hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hnrnpu<tm1.1Tman>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5648110
• Gt(ROSA)26Sor<tm1(CAG-GCaMP5)Ryba>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5649028

class

http://purl.org/net/cito/citesAsAuthority

• Hnrnpu<tm1.1Tman>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5648110
• Gt(ROSA)26Sor<tm1(CAG-GCaMP5)Ryba>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5649028

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardial fiber morphology_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0000278I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• thin ventricular wall_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0000280I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• dilated heart left ventricle_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0002753I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• dilated cardiomyopathy_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0002795I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• dilated cardiomyopathy_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002795I129S4SvJaeSorFVBNHnrnputm11TmanHnrnputm11TmanTgMyh6cre2182Mds0Hnrnputm11TmanTgMyh6cre2182Mds
• increased cardiomyocyte apoptosis_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0003222I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
他15件を見る
• abnormal sarcomere morphology_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0004090I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• abnormal myocardial fiber physiology_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0004215I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• enlarged myocardial fiber_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0004564I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• decreased myocardial fiber number_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0004567I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• decreased cardiac muscle contractility_Gt(ROSA)26Sor<tm1(CAG-GCaMP5)Ryba>/Gt(ROSA)26Sor<+>,Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0005140I129S4SvJaeSorFVBGtROSA26Sortm1CAGGCaMP5RybaGtROSA26SorHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0Hnrnputm11TmanGtROSA26Sortm1CAGGCaMP5RybaTgCkmmcre5KhnGtROSA26Sor
• decreased ventricle muscle contractility_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0005598I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• congestive heart failure_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0006138I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• congestive heart failure_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0006138I129S4SvJaeSorFVBNHnrnputm11TmanHnrnputm11TmanTgMyh6cre2182Mds0Hnrnputm11TmanTgMyh6cre2182Mds
• dilated heart ventricle_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0008022I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• thin interventricular septum_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0010725I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• postnatal lethality, complete penetrance_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0011085I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• postnatal lethality, complete penetrance_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0011085I129S4SvJaeSorFVBNHnrnputm11TmanHnrnputm11TmanTgMyh6cre2182Mds0Hnrnputm11TmanTgMyh6cre2182Mds
• decreased mitochondria number_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0011629I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• abnormal heart echocardiography feature_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0011925I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman
• decreased cardiac muscle relaxation_Hnrnpu<tm1.1Tman>/Hnrnpu<tm1.1Tman>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0020419I129S4SvJaeSorFVBHnrnputm11TmanHnrnputm11TmanTgCkmmcre5Khn0TgCkmmcre5KhnHnrnputm11Tman