Ankush. Gosain, et.al., Impaired Cellular Immunity in the Murine Neural Crest Conditional Deletion of Endothelin Receptor-B Model of Hirschsprung's Disease., PloS one, 2015, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/26061883

Ankush. Gosain, et.al., Impaired Cellular Immunity in the Murine Neural Crest Conditional Deletion of Endothelin Receptor-B Model of Hirschsprung's Disease., PloS one, 2015, 10

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased germinal center B cell number_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0008178I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• abnormal mature B cell number_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0013701I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• small spleen_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000692I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• decreased spleen white pulp amount_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0008479I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• large intestinal inflammation_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0003304I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• abnormal splenic cell ratio_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0008826I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• abnormal Peyer's patch morphology_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000696I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• small Peyer's patches_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0008135I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• decreased spleen weight_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0004953I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• abnormal spleen morphology_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000689I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• decreased IgA level_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0001807I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• decreased marginal zone B cell number_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0008182I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• decreased B cell number_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0005017I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze
• decreased spleen red pulp amount_Ednrb<tm1Nrd>/Ednrb<tm1Nrd>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0008477I129S1Sv129S6SvEvTac129X1SvJC57BL6CBAJEdnrbtm1NrdEdnrbtm1NrdGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgWnt1cre11Rth0GtROSA26SorEdnrbtm1NrdTgWnt1cre11RthGtROSA26Sortm14CAGtdTomatoHze