Leonhard X. Heinz, et.al., The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity., Cell reports, 2015, 11

http://rdf.ncbi.nlm.nih.gov/pubmed/26095358

Leonhard X. Heinz, et.al., The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity., Cell reports, 2015, 11

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating interleukin-12b level_Smpdl3b<tm1a(EUCOMM)Wtsi>/Smpdl3b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008647C57BL6Smpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsi
• abnormal circulating chemokine level_Smpdl3b<tm1a(EUCOMM)Wtsi>/Smpdl3b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0010209C57BL6Smpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsi
• increased circulating interleukin-6 level_Smpdl3b<tm1a(EUCOMM)Wtsi>/Smpdl3b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008596C57BL6Smpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsi
• abnormal chemokine secretion_Smpdl3b<tm1a(EUCOMM)Wtsi>/Smpdl3b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008722C57BL6Smpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsi
• increased neutrophil cell number_Smpdl3b<tm1a(EUCOMM)Wtsi>/Smpdl3b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000219C57BL6Smpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsi
• increased susceptibility to endotoxin shock_Smpdl3b<tm1a(EUCOMM)Wtsi>/Smpdl3b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008735C57BL6Smpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsi
• increased circulating tumor necrosis factor level_Smpdl3b<tm1a(EUCOMM)Wtsi>/Smpdl3b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008553C57BL6Smpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsi
• abnormal macrophage morphology_Smpdl3b<tm1a(EUCOMM)Wtsi>/Smpdl3b<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0002446C57BL6Smpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsiSmpdl3btm1aEUCOMMWtsi