Laura. Braccini, et.al., PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling., Nature communications, 2015, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/26100075

Laura. Braccini, et.al., PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling., Nature communications, 2015, 6

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5779504

class

http://purl.org/net/cito/citesAsAuthority

• Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5779504

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating glucose level_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0005559I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• increased fat cell size_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0006094I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• increased epididymal fat pad weight_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0009288I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• increased circulating insulin level_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0002079I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• insulin resistance_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0005331I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• increased susceptibility to diet-induced obesity_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0005658I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• impaired glucose tolerance_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0005293I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• increased circulating triglyceride level_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0001552I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• increased circulating cholesterol level_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0005178I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• decreased liver glycogen level_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0010398I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• decreased liver weight_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0003402I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• increased body weight_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0001260I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi
• hepatic steatosis_Pik3c2g<tm1Ehi>/Pik3c2g<tm1Ehi>
  http://metadb.riken.jp/0002628I129C57BL6Pik3c2gtm1EhiPik3c2gtm1EhiPik3c2gtm1Ehi