Brynn N. Akerberg, et.al., Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease., Developmental biology, 2015, 407

http://rdf.ncbi.nlm.nih.gov/pubmed/26100917

Brynn N. Akerberg, et.al., Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease., Developmental biology, 2015, 407

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal pulmonary valve cusp morphology_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010602I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• enlarged heart_Nfatc1<tm1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0000274I129S1Sv129S2SvPas129X1SvJNfatc1tm1creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1tm1creBzNfatc1Smarca4tm12Pcn
• thick heart valve cusps_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0011648I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• abnormal aortic valve morphology_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0002747I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• abnormal cardiac outflow tract development_Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0006126I129S2SvPasC57BL6SJLSmarca4tm12PcnSmarca4tm12PcnTgTekcre1Ywa0Smarca4tm12PcnTgTekcre1Ywa
• cardiomyopathy_Nfatc1<tm1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0005330I129S1Sv129S2SvPas129X1SvJNfatc1tm1creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1tm1creBzNfatc1Smarca4tm12Pcn
• thick myocardium_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010656I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• thick pulmonary valve_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010601I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• abnormal aortic valve cusp morphology_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010595I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• abnormal semilunar valve morphology_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0002746I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• lethality throughout fetal growth and development, incomplete penetrance_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0011109I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• abnormal coronary vein morphology_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010453I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• perinatal lethality_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0002081I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• bicuspid aortic valve_Nfatc1<tm1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010484I129S1Sv129S2SvPas129X1SvJNfatc1tm1creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1tm1creBzNfatc1Smarca4tm12Pcn
• abnormal heart ventricle morphology_Nfatc1<tm1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0005294I129S1Sv129S2SvPas129X1SvJNfatc1tm1creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1tm1creBzNfatc1Smarca4tm12Pcn
• perimembraneous ventricular septal defect_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010418I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• abnormal cardiac outflow tract development_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0006126I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• abnormal aortic sinus morphology_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010482I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• abnormal coronary artery morphology_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0004111I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• abnormal atrioventricular cushion morphology_Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000297I129S2SvPasC57BL6SJLSmarca4tm12PcnSmarca4tm12PcnTgTekcre1Ywa0Smarca4tm12PcnTgTekcre1Ywa
• abnormal aortic valve morphology_Nfatc1<tm1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0002747I129S1Sv129S2SvPas129X1SvJNfatc1tm1creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1tm1creBzNfatc1Smarca4tm12Pcn
• thick aortic valve cusps_Nfatc1<tm1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010593I129S1Sv129S2SvPas129X1SvJNfatc1tm1creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1tm1creBzNfatc1Smarca4tm12Pcn
• enlarged heart_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0000274I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• thick aortic valve_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010594I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• abnormal semilunar valve morphology_Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/Gt(ROSA)26Sor<+>,Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0002746I129S1Sv129S2SvPas129X1SvJGtROSA26Sortm4ACTBtdTomatoEGFPLuoGtROSA26SorNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnGtROSA26SorNfatc1tm11creBzSmarca4tm12PcnNfatc1GtROSA26Sortm4ACTBtdTomatoEGFPLuo
• bicuspid aortic valve_Nfatc1<tm1.1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010484I129S1Sv129S2SvPas129X1SvJNfatc1tm11creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1Smarca4tm12PcnNfatc1tm11creBz
• thick pulmonary valve_Nfatc1<tm1(cre)Bz>/Nfatc1<+>,Smarca4<tm1.2Pcn>/Smarca4<tm1.2Pcn>
  http://metadb.riken.jp/0010601I129S1Sv129S2SvPas129X1SvJNfatc1tm1creBzNfatc1Smarca4tm12PcnSmarca4tm12PcnNfatc1tm1creBzNfatc1Smarca4tm12Pcn