Marko. Marjanović, et.al., CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination., Nature communications, 2015, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/26158450

Marko. Marjanović, et.al., CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination., Nature communications, 2015, 6

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased testis weight_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0004852I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal spermatogonia morphology_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0006378I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal male meiosis_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0005169I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal synaptonemal complex_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0009452I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal spermatocyte morphology_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0006379I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• postnatal growth retardation_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0001732I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• decreased body weight_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0001262I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• thin cerebral cortex_Atm<tm1Awb>/Atm<tm1Awb>,Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0006254I129P2OlaHsd129S6SvEvTacC57BL6Atmtm1AwbAtmtm1AwbCep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguAtmtm1Awb
• increased testis apoptosis_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0013601I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal double-strand DNA break repair_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0010948I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal testis development_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0003830I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal cortical ventricular zone morphology_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0008458I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• increased forebrain apoptosis_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0012504I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• testis hypoplasia_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0001940I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal telomere morphology_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0010207I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal spermatid morphology_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0006380I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• polyploidy_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0004025I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• thin cerebral cortex_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>,Chek2<tm1Mak>/Chek2<tm1Mak>
  http://metadb.riken.jp/0006254I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguChek2tm1MakChek2tm1MakCep63GtEUCE0251h11HmguChek2tm1Mak
• decreased oocyte number_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0005431I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• azoospermia_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0005159I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal spermatogenesis_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0001156I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal mitosis_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0004046I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• small testis_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0001147I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• thin cerebral cortex_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0006254I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• small seminiferous tubules_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0001153I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• decreased forebrain size_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0012138I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal mitotic spindle morphology_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0009760I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• microcephaly_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0000433I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• male infertility_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0001925I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• abnormal cerebral cortex morphology_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0000788I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu
• decreased neuronal precursor cell number_Cep63<Gt(EUCE0251h11)Hmgu>/Cep63<Gt(EUCE0251h11)Hmgu>
  http://metadb.riken.jp/0004981I129P2OlaHsd129SSvEvC57BL6Cep63GtEUCE0251h11HmguCep63GtEUCE0251h11HmguCep63GtEUCE0251h11Hmgu