Lawrence R. Gray, et.al., Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis., Cell metabolism, 2015, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/26344103

Lawrence R. Gray, et.al., Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis., Cell metabolism, 2015, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mpc1<tm1c(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5903307

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating lactate level_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0013405IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• decreased circulating glucose level_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005560IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• abnormal mitochondrial physiology_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0006036IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• increased insulin sensitivity_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>
  http://metadb.riken.jp/0002891IC57BL6JC57BL6NMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsi
• increased circulating ketone body level_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002575IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• improved glucose tolerance_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005292IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• abnormal gluconeogenesis_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003383IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• decreased circulating triglyceride level_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002644IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• decreased circulating cholesterol level_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005179IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• increased fatty acid oxidation_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0014171IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• improved glucose tolerance_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>
  http://metadb.riken.jp/0005292IC57BL6JC57BL6NMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsi
• increased triglyceride level_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005317IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• decreased body weight_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001262IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi
• decreased respiratory quotient_Mpc1<tm1c(EUCOMM)Wtsi>/Mpc1<tm1c(EUCOMM)Wtsi>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0010379IC57BL6C57BL6JC57BL6NDBAMpc1tm1cEUCOMMWtsiMpc1tm1cEUCOMMWtsiTgAlbcre21Mgn0TgAlbcre21MgnMpc1tm1cEUCOMMWtsi

class

http://purl.org/net/cito/citesAsAuthority

• Mpc1<tm1c(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5903307