Christopher T. Pappas, et.al., Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112

http://rdf.ncbi.nlm.nih.gov/pubmed/26487682

Christopher T. Pappas, et.al., Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart ventricle morphology_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0005294IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• postnatal lethality, incomplete penetrance_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0011086IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• abnormal myocardial fiber morphology_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0000278IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• thin ventricular wall_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0000280IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• decreased mitochondria number_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0011629IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• premature death_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002083IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• abnormal fetal cardiomyocyte morphology_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0008788IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• dilated cardiomyopathy_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002795IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• decreased cardiac muscle contractility_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0005140IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• increased heart weight_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002833IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• abnormal Z lines_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0004091IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• abnormal sarcomere morphology_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0004090IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• abnormal intercalated disc morphology_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0006267IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• dilated heart left ventricle_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0002753IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg
• dilated heart_Lmod2<tm1(KOMP)Vlcg>/Lmod2<tm1(KOMP)Vlcg>
  http://metadb.riken.jp/0004937IC57BL6JC57BL6NTacLmod2tm1KOMPVlcgLmod2tm1KOMPVlcgLmod2tm1KOMPVlcg