Helena. Maier, et.al., N-Acetylaspartate Synthase Deficiency Corrects the Myelin Phenotype in a Canavan Disease Mouse Model But Does Not Affect Survival Time., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, 35

http://rdf.ncbi.nlm.nih.gov/pubmed/26511242

Helena. Maier, et.al., N-Acetylaspartate Synthase Deficiency Corrects the Myelin Phenotype in a Canavan Disease Mouse Model But Does Not Affect Survival Time., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, 35

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nat8l<tm1.2Meck>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5771691
• Nat8l<tm1.1Meck>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5771690

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased vertical activity_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0002757IC57BL6JAspanur7Aspanur7Aspanur7
• astrocytosis_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0003354IC57BL6JAspanur7Aspanur7Aspanur7
• spongiform encephalopathy_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<+>
  http://metadb.riken.jp/0002654I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8lAspanur7Nat8lNat8ltm12Meck
• spongiform encephalopathy_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0002654IC57BL6JAspanur7Aspanur7Aspanur7
• premature death_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<tm1.2Meck>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8ltm12MeckAspanur7Nat8ltm12Meck
• hypoactivity_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<+>
  http://metadb.riken.jp/0001402I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8lAspanur7Nat8lNat8ltm12Meck
• abnormal enzyme/coenzyme activity_Nat8l<tm1.2Meck>/Nat8l<tm1.2Meck>
  http://metadb.riken.jp/0005584I129P2OlaHsdC57BL6Nat8ltm12MeckNat8ltm12MeckNat8ltm12Meck
• abnormal brain morphology_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<+>
  http://metadb.riken.jp/0002152I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8lAspanur7Nat8lNat8ltm12Meck
• abnormal sphingolipid level_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0012230IC57BL6JAspanur7Aspanur7Aspanur7
• abnormal enzyme/coenzyme level_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0005319IC57BL6JAspanur7Aspanur7Aspanur7
• abnormal enzyme/coenzyme level_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<+>
  http://metadb.riken.jp/0005319I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8lAspanur7Nat8lNat8ltm12Meck
• abnormal astrocyte morphology_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<tm1.2Meck>
  http://metadb.riken.jp/0002182I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8ltm12MeckAspanur7Nat8ltm12Meck
• abnormal enzyme/coenzyme level_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<tm1.2Meck>
  http://metadb.riken.jp/0005319I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8ltm12MeckAspanur7Nat8ltm12Meck
• decreased body weight_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<+>
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8lAspanur7Nat8lNat8ltm12Meck
• abnormal brain morphology_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0002152IC57BL6JAspanur7Aspanur7Aspanur7
• premature death_Nat8l<tm1.2Meck>/Nat8l<tm1.2Meck>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Nat8ltm12MeckNat8ltm12MeckNat8ltm12Meck
• tremors_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0000745IC57BL6JAspanur7Aspanur7Aspanur7
• brain vacuoles_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0008025IC57BL6JAspanur7Aspanur7Aspanur7
• premature death_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0002083IC57BL6JAspanur7Aspanur7Aspanur7
• decreased vertical activity_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<+>
  http://metadb.riken.jp/0002757I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8lAspanur7Nat8lNat8ltm12Meck
• ataxia_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0001393IC57BL6JAspanur7Aspanur7Aspanur7
• decreased body weight_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0001262IC57BL6JAspanur7Aspanur7Aspanur7
• abnormal enzyme/coenzyme level_Nat8l<tm1.2Meck>/Nat8l<tm1.2Meck>
  http://metadb.riken.jp/0005319I129P2OlaHsdC57BL6Nat8ltm12MeckNat8ltm12MeckNat8ltm12Meck
• impaired coordination_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0001405IC57BL6JAspanur7Aspanur7Aspanur7
• axon degeneration_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0005405IC57BL6JAspanur7Aspanur7Aspanur7
• abnormal brain white matter morphology_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0008026IC57BL6JAspanur7Aspanur7Aspanur7
• seizures_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0002064IC57BL6JAspanur7Aspanur7Aspanur7
• abnormal brain morphology_Nat8l<tm1.2Meck>/Nat8l<tm1.2Meck>
  http://metadb.riken.jp/0002152I129P2OlaHsdC57BL6Nat8ltm12MeckNat8ltm12MeckNat8ltm12Meck
• astrocytosis_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<+>
  http://metadb.riken.jp/0003354I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8lAspanur7Nat8lNat8ltm12Meck
• brain vacuoles_Aspa<nur7>/Aspa<nur7>,Nat8l<tm1.2Meck>/Nat8l<+>
  http://metadb.riken.jp/0008025I129P2OlaHsdC57BL6C57BL6JAspanur7Aspanur7Nat8ltm12MeckNat8lAspanur7Nat8lNat8ltm12Meck
• hypoactivity_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0001402IC57BL6JAspanur7Aspanur7Aspanur7
• demyelination_Aspa<nur7>/Aspa<nur7>
  http://metadb.riken.jp/0000921IC57BL6JAspanur7Aspanur7Aspanur7

class

http://purl.org/net/cito/citesAsAuthority

• Nat8l<tm1.2Meck>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5771691
• Nat8l<tm1.1Meck>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5771690