Kenta. Moriwaki, et.al., The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages., Journal of immunology (Baltimore, Md. : 1950), 2016, 196

http://rdf.ncbi.nlm.nih.gov/pubmed/26582950

Kenta. Moriwaki, et.al., The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages., Journal of immunology (Baltimore, Md. : 1950), 2016, 196

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pgam5<tm1c(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5882559
• Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5882561

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body weight_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001262IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi
• decreased interleukin-1 beta secretion_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008658IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi
• premature death_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0002083IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi
• abnormal mitochondrial shape_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0011633IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi
• abnormal interleukin-1 beta secretion_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008656IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi
• abnormal macrophage activation involved in immune response_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0011075IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi
• abnormal mitochondrion morphology_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0006035IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi
• abnormal redox activity_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0003186IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi
• decreased survivor rate_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008770IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi
• prenatal lethality, incomplete penetrance_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0011101IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi
• decreased body size_Pgam5<tm1d(EUCOMM)Wtsi>/Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001265IC57BL6NPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsiPgam5tm1dEUCOMMWtsi

class

http://purl.org/net/cito/citesAsAuthority

• Pgam5<tm1c(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5882559
• Pgam5<tm1d(EUCOMM)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5882561