Elaine. Wan, et.al., Aberrant sodium influx causes cardiomyopathy and atrial fibrillation in mice., The Journal of clinical investigation, 2016, 126

http://rdf.ncbi.nlm.nih.gov/pubmed/26595809

Elaine. Wan, et.al., Aberrant sodium influx causes cardiomyopathy and atrial fibrillation in mice., The Journal of clinical investigation, 2016, 126

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6*/tetO-SCN5A*F1759A)#Marx
  http://metadb.riken.jp/db/mgi_rdf/MGI:5800483

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged heart atrium_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0008725IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• abnormal myocardial fiber currents_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0020345IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• abnormal mycoardial fiber sodium currents_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0020347IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• prolonged QT interval_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0003233IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• abnormal heart ventricle morphology_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0005294IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• cardiomyopathy_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0005330IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• increased cardiac muscle glycogen level_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0014071IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• enlarged heart left atrium_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0008726IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• abnormal heart atrium morphology_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0003105IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• ventricular tachycardia_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0008950IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• abnormal myocardial fiber morphology_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0000278IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• decreased ventricle muscle contractility_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0005598IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• atrial fibrillation_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0008543IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• increased heart ventricle size_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0008772IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• cardiac fibrosis_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0003141IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam
• ventricular premature beat_Tg(Myh6-rtTA)8585Jam/0,Tg(Myh6*/tetO-SCN5A*F1759A)#Marx/0
  http://metadb.riken.jp/0009732IC57BL6CBAFVBNTacTgMyh6rtTA8585Jam0TgMyh6tetOSCN5AF1759AMarx0TgMyh6tetOSCN5AF1759AMarxTgMyh6rtTA8585Jam

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6*/tetO-SCN5A*F1759A)#Marx
  http://metadb.riken.jp/db/mgi_rdf/MGI:5800483