Nicolas. Casadei, et.al., Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2., Human molecular genetics, 2016, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/26604148

Nicolas. Casadei, et.al., Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2., Human molecular genetics, 2016, 25

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-HTRA2)1Olri
  http://metadb.riken.jp/db/mgi_rdf/MGI:5790704
• Tg(Prnp-HTRA2*G399S)1Olri
  http://metadb.riken.jp/db/mgi_rdf/MGI:5790703

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cerebellum morphology_Tg(Prnp-HTRA2)1Olri/0
  http://metadb.riken.jp/0000849IC57BL6TgPrnpHTRA21Olri0TgPrnpHTRA21Olri
• abnormal mitochondrial physiology_Tg(Prnp-HTRA2*G399S)1Olri/0
  http://metadb.riken.jp/0006036IC57BL6TgPrnpHTRA2G399S1Olri0TgPrnpHTRA2G399S1Olri
• impaired coordination_Tg(Prnp-HTRA2)1Olri/0
  http://metadb.riken.jp/0001405IC57BL6TgPrnpHTRA21Olri0TgPrnpHTRA21Olri
• abnormal mitochondrial physiology_Tg(Prnp-HTRA2)1Olri/0
  http://metadb.riken.jp/0006036IC57BL6TgPrnpHTRA21Olri0TgPrnpHTRA21Olri
• abnormal cell physiology_Tg(Prnp-HTRA2)1Olri/0
  http://metadb.riken.jp/0005621IC57BL6TgPrnpHTRA21Olri0TgPrnpHTRA21Olri
• loss of dopaminergic neurons_Tg(Prnp-HTRA2)1Olri/0
  http://metadb.riken.jp/0003244IC57BL6TgPrnpHTRA21Olri0TgPrnpHTRA21Olri
• impaired balance_Tg(Prnp-HTRA2)1Olri/0
  http://metadb.riken.jp/0001525IC57BL6TgPrnpHTRA21Olri0TgPrnpHTRA21Olri
• abnormal motor learning_Tg(Prnp-HTRA2)1Olri/0
  http://metadb.riken.jp/0002804IC57BL6TgPrnpHTRA21Olri0TgPrnpHTRA21Olri

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-HTRA2)1Olri
  http://metadb.riken.jp/db/mgi_rdf/MGI:5790704
• Tg(Prnp-HTRA2*G399S)1Olri
  http://metadb.riken.jp/db/mgi_rdf/MGI:5790703