Maria. Traka, et.al., Oligodendrocyte death results in immune-mediated CNS demyelination., Nature neuroscience, 2016, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/26656646

Maria. Traka, et.al., Oligodendrocyte death results in immune-mediated CNS demyelination., Nature neuroscience, 2016, 19

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal motor coordination/ balance_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0001516I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• seizures_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0002064I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• autoimmune response_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0001844I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• premature death_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0002083I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• weight loss_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0001263I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• demyelination_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0000921I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• decreased myelin sheath thickness_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0011731I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• CNS inflammation_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0006082I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• abnormal brain white matter morphology_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0008026I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• axon degeneration_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0005405I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• abnormal nervous system morphology_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0003632I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• increased activated T cell number_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0001829I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• ataxia_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0001393I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• decreased oligodendrocyte number_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0009808I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop
• lymph node inflammation_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Plp1-cre/ERT)3Pop/0
  http://metadb.riken.jp/0003865I129SSvEvC57BL6DBA2GtROSA26Sortm1DTAJpmbGtROSA26SorTgPlp1creERT3Pop0GtROSA26SorGtROSA26Sortm1DTAJpmbTgPlp1creERT3Pop