Timothy. Wai, et.al., Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice., Science (New York, N.Y.), 2015, 350

http://rdf.ncbi.nlm.nih.gov/pubmed/26785494

Timothy. Wai, et.al., Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice., Science (New York, N.Y.), 2015, 350

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating insulin level_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0002727IC57BL6C57BL6NCrlFVBYme1l1tm1TlanYme1l1tm1TlanTgCkmmcre5Khn0TgCkmmcre5KhnYme1l1tm1Tlan
• dilated cardiomyopathy_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002795IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• cardiac fibrosis_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0003141IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• decreased mitochondria size_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0011631IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• abnormal mitochondrion morphology_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0006035IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• cardiac muscle necrosis_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0010632IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• abnormal mitochondrial physiology_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0006036IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• decreased ventricle muscle contractility_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0005598IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• weight loss_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0001263IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• dilated heart left ventricle_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002753IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• impaired glucose tolerance_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0005293IC57BL6C57BL6NCrlFVBYme1l1tm1TlanYme1l1tm1TlanTgCkmmcre5Khn0TgCkmmcre5KhnYme1l1tm1Tlan
• abnormal muscle physiology_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002106IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• abnormal blood homeostasis_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0009642IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• abnormal cardiovascular system physiology_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0001544IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• increased cardiac cell glucose uptake_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0030018IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• premature death_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002083IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds
• abnormal heart morphology_Yme1l1<tm1Tlan>/Yme1l1<tm1Tlan>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0000266IC57BL6C57BL6NCrlFVBNYme1l1tm1TlanYme1l1tm1TlanTgMyh6cre2182Mds0Yme1l1tm1TlanTgMyh6cre2182Mds