Siang-Yun. Ang, et.al., KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation., Development (Cambridge, England), 2016, 143

http://rdf.ncbi.nlm.nih.gov/pubmed/26932671

Siang-Yun. Ang, et.al., KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation., Development (Cambridge, England), 2016, 143

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased fetal cardiomyocyte proliferation_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tg(Tnnt2-cre)5Blh/0
  http://metadb.riken.jp/0011395B6CgKmt2dtm11KaigTgTnnt2cre5BlhKmt2dtm11KaigKmt2dtm11KaigTgTnnt2cre5Blh0Kmt2dtm11KaigTgTnnt2cre5Blh
• thin myocardium compact layer_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tg(Tnnt2-cre)5Blh/0
  http://metadb.riken.jp/0004057B6CgKmt2dtm11KaigTgTnnt2cre5BlhKmt2dtm11KaigKmt2dtm11KaigTgTnnt2cre5Blh0Kmt2dtm11KaigTgTnnt2cre5Blh
• abnormal fetal cardiomyocyte morphology_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tg(Tnnt2-cre)5Blh/0
  http://metadb.riken.jp/0008788B6CgKmt2dtm11KaigTgTnnt2cre5BlhKmt2dtm11KaigKmt2dtm11KaigTgTnnt2cre5Blh0Kmt2dtm11KaigTgTnnt2cre5Blh
• absent somites_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tmem163<Tg(ACTB-cre)2Mrt>/0
  http://metadb.riken.jp/0006386B6CgKmt2dtm11KaigTgACTBcre2MrtKmt2dtm11KaigKmt2dtm11KaigTmem163TgACTBcre2Mrt0Kmt2dtm11KaigTmem163TgACTBcre2Mrt
• embryonic lethality during organogenesis, complete penetrance_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0011098B6CgMesp1tm2creYsaKmt2dtm11KaigKmt2dtm11KaigKmt2dtm11KaigMesp1tm2creYsaMesp1Mesp1Mesp1tm2creYsaKmt2dtm11Kaig
• embryonic lethality during organogenesis, complete penetrance_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0011098B6CgKmt2dtm11KaigTgMef2ccre2BlkKmt2dtm11KaigKmt2dtm11KaigTgMef2ccre2Blk0Kmt2dtm11KaigTgMef2ccre2Blk
• abnormal interventricular septum morphology_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0000281B6CgKmt2dtm11KaigTgMef2ccre2BlkKmt2dtm11KaigKmt2dtm11KaigTgMef2ccre2Blk0Kmt2dtm11KaigTgMef2ccre2Blk
• abnormal heart echocardiography feature_Kmt2d<tm1.1Kaig>/Kmt2d<+>,Tmem163<Tg(ACTB-cre)2Mrt>/0
  http://metadb.riken.jp/0011925B6CgKmt2dtm11KaigTgACTBcre2MrtKmt2dtm11KaigKmt2dTmem163TgACTBcre2Mrt0Tmem163TgACTBcre2MrtKmt2dtm11KaigKmt2d
• abnormal heart tube morphology_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0000270B6CgMesp1tm2creYsaKmt2dtm11KaigKmt2dtm11KaigKmt2dtm11KaigMesp1tm2creYsaMesp1Mesp1Mesp1tm2creYsaKmt2dtm11Kaig
• embryonic growth retardation_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0003984B6CgMesp1tm2creYsaKmt2dtm11KaigKmt2dtm11KaigKmt2dtm11KaigMesp1tm2creYsaMesp1Mesp1Mesp1tm2creYsaKmt2dtm11Kaig
• abnormal interventricular septum morphology_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tg(Tnnt2-cre)5Blh/0
  http://metadb.riken.jp/0000281B6CgKmt2dtm11KaigTgTnnt2cre5BlhKmt2dtm11KaigKmt2dtm11KaigTgTnnt2cre5Blh0Kmt2dtm11KaigTgTnnt2cre5Blh
• pericardial edema_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0001787B6CgMesp1tm2creYsaKmt2dtm11KaigKmt2dtm11KaigKmt2dtm11KaigMesp1tm2creYsaMesp1Mesp1Mesp1tm2creYsaKmt2dtm11Kaig
• persistent truncus arteriosis_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0002633B6CgKmt2dtm11KaigTgMef2ccre2BlkKmt2dtm11KaigKmt2dtm11KaigTgMef2ccre2Blk0Kmt2dtm11KaigTgMef2ccre2Blk
• embryonic lethality during organogenesis, complete penetrance_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tg(Tnnt2-cre)5Blh/0
  http://metadb.riken.jp/0011098B6CgKmt2dtm11KaigTgTnnt2cre5BlhKmt2dtm11KaigKmt2dtm11KaigTgTnnt2cre5Blh0Kmt2dtm11KaigTgTnnt2cre5Blh
• embryonic lethality between somite formation and embryo turning, complete penetrance_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tmem163<Tg(ACTB-cre)2Mrt>/0
  http://metadb.riken.jp/0011097B6CgKmt2dtm11KaigTgACTBcre2MrtKmt2dtm11KaigKmt2dtm11KaigTmem163TgACTBcre2Mrt0Kmt2dtm11KaigTmem163TgACTBcre2Mrt
• absent head fold_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Tmem163<Tg(ACTB-cre)2Mrt>/0
  http://metadb.riken.jp/0012724B6CgKmt2dtm11KaigTgACTBcre2MrtKmt2dtm11KaigKmt2dtm11KaigTmem163TgACTBcre2Mrt0Kmt2dtm11KaigTmem163TgACTBcre2Mrt