Trevelyan R. Menheniott, et.al., Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression., The Journal of clinical investigation, 2016, 126

http://rdf.ncbi.nlm.nih.gov/pubmed/26974160

Trevelyan R. Menheniott, et.al., Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression., The Journal of clinical investigation, 2016, 126

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(RP11-H2112)9Trme
  http://metadb.riken.jp/db/mgi_rdf/MGI:5898086
• Tg(RP11-H2112)5Trme
  http://metadb.riken.jp/db/mgi_rdf/MGI:5898085

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased susceptibility to bacterial infection_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0002412IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• abnormal stomach mucosa morphology_Il6st<tm1Ern>/Il6st<tm1Ern>,Tg(RP11-H2112)9Trme/0
  http://metadb.riken.jp/0010792I129S1SvC57BL6JDBA2JIl6sttm1ErnIl6sttm1ErnTgRP11H21129Trme0TgRP11H21129TrmeIl6sttm1Ern
• abnormal cytokine level_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0008713IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• abnormal digestive system physiology_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0001663IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• abnormal chemokine level_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0008721IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• abnormal T-helper 1 physiology_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0005465IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• increased stomach tumor incidence_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>,Il6st<tm1Ern>/Il6st<tm1Ern>
  http://metadb.riken.jp/0010301I129S1SvC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgIl6sttm1ErnIl6sttm1ErnIl6sttm1ErnGkn2tm11KOMPVlcg
• abnormal stomach mucosa morphology_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0010792IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• increased stomach mucosa thickness_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>,Il6st<tm1Ern>/Il6st<tm1Ern>
  http://metadb.riken.jp/0005211I129S1SvC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgIl6sttm1ErnIl6sttm1ErnIl6sttm1ErnGkn2tm11KOMPVlcg
• abnormal spleen size_Il6st<tm1Ern>/Il6st<tm1Ern>,Tg(RP11-H2112)9Trme/0
  http://metadb.riken.jp/0002224I129S1SvC57BL6JDBA2JIl6sttm1ErnIl6sttm1ErnTgRP11H21129Trme0TgRP11H21129TrmeIl6sttm1Ern
• abnormal innate immunity_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0002419IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• decreased myeloid cell number_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0013662IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• altered susceptibility to bacterial infection_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0020186IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• abnormal spleen size_Il6st<tm1Ern>/Il6st<tm1Ern>,Tg(RP11-H2112)5Trme/0
  http://metadb.riken.jp/0002224I129S1SvC57BL6JDBA2JIl6sttm1ErnIl6sttm1ErnTgRP11H21125Trme0Il6sttm1ErnTgRP11H21125Trme
• gastric gland atrophy_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0013567IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• decreased stomach tumor incidence_Il6st<tm1Ern>/Il6st<tm1Ern>,Tg(RP11-H2112)5Trme/0
  http://metadb.riken.jp/0010270I129S1SvC57BL6JDBA2JIl6sttm1ErnIl6sttm1ErnTgRP11H21125Trme0Il6sttm1ErnTgRP11H21125Trme
• abnormal cell differentiation_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0005076IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• abnormal tumor necrosis factor level_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0008752IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• abnormal interleukin level_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0008751IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• decreased stomach tumor incidence_Il6st<tm1Ern>/Il6st<tm1Ern>,Tg(RP11-H2112)9Trme/0
  http://metadb.riken.jp/0010270I129S1SvC57BL6JDBA2JIl6sttm1ErnIl6sttm1ErnTgRP11H21129Trme0TgRP11H21129TrmeIl6sttm1Ern
• stomach inflammation_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>
  http://metadb.riken.jp/0001873IC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgGkn2tm11KOMPVlcg
• abnormal stomach mucosa morphology_Gkn2<tm1.1(KOMP)Vlcg>/Gkn2<tm1.1(KOMP)Vlcg>,Il6st<tm1Ern>/Il6st<tm1Ern>
  http://metadb.riken.jp/0010792I129S1SvC57BL6NTacGkn2tm11KOMPVlcgGkn2tm11KOMPVlcgIl6sttm1ErnIl6sttm1ErnIl6sttm1ErnGkn2tm11KOMPVlcg
• abnormal stomach mucosa morphology_Il6st<tm1Ern>/Il6st<tm1Ern>,Tg(RP11-H2112)5Trme/0
  http://metadb.riken.jp/0010792I129S1SvC57BL6JDBA2JIl6sttm1ErnIl6sttm1ErnTgRP11H21125Trme0Il6sttm1ErnTgRP11H21125Trme

class

http://purl.org/net/cito/citesAsAuthority

• Tg(RP11-H2112)9Trme
  http://metadb.riken.jp/db/mgi_rdf/MGI:5898086
• Tg(RP11-H2112)5Trme
  http://metadb.riken.jp/db/mgi_rdf/MGI:5898085