Daniel R. Dries, et.al., Loss of Nicastrin from Oligodendrocytes Results in Hypomyelination and Schizophrenia with Compulsive Behavior., The Journal of biological chemistry, 2016, 291

http://rdf.ncbi.nlm.nih.gov/pubmed/27008863

Daniel R. Dries, et.al., Loss of Nicastrin from Oligodendrocytes Results in Hypomyelination and Schizophrenia with Compulsive Behavior., The Journal of biological chemistry, 2016, 291

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased exploration in new environment_Ncstn<tm1.1Sud>/Ncstn<tm1.1Sud>,Olig1<tm1(cre)Rth>/Olig1<+>
  http://metadb.riken.jp/0001415I129S1Sv129S4SvJae129X1SvJNcstntm11SudNcstntm11SudOlig1tm1creRthOlig1Ncstntm11SudOlig1Olig1tm1creRth
• dysmyelination_Ncstn<tm1.1Sud>/Ncstn<tm1.1Sud>,Olig1<tm1(cre)Rth>/Olig1<+>
  http://metadb.riken.jp/0013438I129S1Sv129S4SvJae129X1SvJNcstntm11SudNcstntm11SudOlig1tm1creRthOlig1Ncstntm11SudOlig1Olig1tm1creRth
• hyperactivity_Ncstn<tm1.1Sud>/Ncstn<tm1.1Sud>,Olig1<tm1(cre)Rth>/Olig1<+>
  http://metadb.riken.jp/0001399I129S1Sv129S4SvJae129X1SvJNcstntm11SudNcstntm11SudOlig1tm1creRthOlig1Ncstntm11SudOlig1Olig1tm1creRth
• increased stereotypic behavior_Ncstn<tm1.1Sud>/Ncstn<tm1.1Sud>,Olig1<tm1(cre)Rth>/Olig1<+>
  http://metadb.riken.jp/0001409I129S1Sv129S4SvJae129X1SvJNcstntm11SudNcstntm11SudOlig1tm1creRthOlig1Ncstntm11SudOlig1Olig1tm1creRth
• skin lesions_Ncstn<tm1.1Sud>/Ncstn<tm1.1Sud>,Olig1<tm1(cre)Rth>/Olig1<+>
  http://metadb.riken.jp/0001212I129S1Sv129S4SvJae129X1SvJNcstntm11SudNcstntm11SudOlig1tm1creRthOlig1Ncstntm11SudOlig1Olig1tm1creRth
• decreased myelin sheath thickness_Ncstn<tm1.1Sud>/Ncstn<tm1.1Sud>,Olig1<tm1(cre)Rth>/Olig1<+>
  http://metadb.riken.jp/0011731I129S1Sv129S4SvJae129X1SvJNcstntm11SudNcstntm11SudOlig1tm1creRthOlig1Ncstntm11SudOlig1Olig1tm1creRth
• abnormal coat appearance_Ncstn<tm1.1Sud>/Ncstn<tm1.1Sud>,Olig1<tm1(cre)Rth>/Olig1<+>
  http://metadb.riken.jp/0001510I129S1Sv129S4SvJae129X1SvJNcstntm11SudNcstntm11SudOlig1tm1creRthOlig1Ncstntm11SudOlig1Olig1tm1creRth
• increased grooming behavior_Ncstn<tm1.1Sud>/Ncstn<tm1.1Sud>,Olig1<tm1(cre)Rth>/Olig1<+>
  http://metadb.riken.jp/0001441I129S1Sv129S4SvJae129X1SvJNcstntm11SudNcstntm11SudOlig1tm1creRthOlig1Ncstntm11SudOlig1Olig1tm1creRth
• decreased prepulse inhibition_Ncstn<tm1.1Sud>/Ncstn<tm1.1Sud>,Olig1<tm1(cre)Rth>/Olig1<+>
  http://metadb.riken.jp/0009142I129S1Sv129S4SvJae129X1SvJNcstntm11SudNcstntm11SudOlig1tm1creRthOlig1Ncstntm11SudOlig1Olig1tm1creRth