Eriks. Smagris, et.al., Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins., The Journal of biological chemistry, 2016, 291

http://rdf.ncbi.nlm.nih.gov/pubmed/27013658

Eriks. Smagris, et.al., Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins., The Journal of biological chemistry, 2016, 291

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased intestinal cholesterol absorption_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0002647C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• hepatic steatosis_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0002628C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• increased triglyceride level_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0005317C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• increased circulating triglyceride level_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001552C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• abnormal circulating apolipoprotein level_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0010332C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• abnormal cholesterol homeostasis_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<+>
  http://metadb.riken.jp/0005278C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2Tm6sf2tm1aKOMPWtsiTm6sf2
• increased liver triglyceride level_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0009355C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• abnormal intestinal lipid absorption_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0005342C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• increased liver triglyceride level_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<+>
  http://metadb.riken.jp/0009355C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2Tm6sf2tm1aKOMPWtsiTm6sf2
• abnormal enterocyte morphology_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0000479C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• decreased circulating LDL cholesterol level_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0000183C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• increased circulating alanine transaminase level_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0002941C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• decreased circulating HDL cholesterol level_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0000186C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• decreased circulating VLDL triglyceride level_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0003976C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• decreased circulating cholesterol level_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0005179C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi
• abnormal cholesterol homeostasis_Tm6sf2<tm1a(KOMP)Wtsi>/Tm6sf2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0005278C57BL6NTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsiTm6sf2tm1aKOMPWtsi