Milena. Pinto, et.al., Pioglitazone ameliorates the phenotype of a novel Parkinson's disease mouse model by reducing neuroinflammation., Molecular neurodegeneration, 2016, 11

http://rdf.ncbi.nlm.nih.gov/pubmed/27038906

Milena. Pinto, et.al., Pioglitazone ameliorates the phenotype of a novel Parkinson's disease mouse model by reducing neuroinflammation., Molecular neurodegeneration, 2016, 11

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal microglial cell activation_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0010762B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• decreased dopaminergic neuron number_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0011448B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• impaired coordination_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0001405B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• decreased dopamine level_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0005643B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• decreased body weight_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0001262B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• abnormal motor capabilities/coordination/movement_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0002066B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• loss of dopaminergic neurons_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0003244B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• hypoactivity_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0001402B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• microgliosis_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0008918B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• decreased vertical activity_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0002757B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• abnormal chemokine secretion_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0008722B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn
• increased interleukin-1 beta secretion_Cox10<tm1Ctm>/Cox10<tm1Ctm>,Slc6a3<tm1.1(cre)Bkmn>/?
  http://metadb.riken.jp/0008657B6CgCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmCox10tm1CtmSlc6a3tm11creBkmnCox10tm1CtmSlc6a3tm11creBkmn