Kifayathullah. Liakath-Ali, et.al., Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole-body energy expenditure., The Journal of pathology, 2016, 239

http://rdf.ncbi.nlm.nih.gov/pubmed/27126290

Kifayathullah. Liakath-Ali, et.al., Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole-body energy expenditure., The Journal of pathology, 2016, 239

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• alopecia_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000414C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal lipid level_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001547C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• increased food intake_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0011939C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• decreased brown adipose tissue mass_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0014169C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• decreased body weight_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001262C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• hyperactivity_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001399C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal zigzag hair morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000402C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• increased energy expenditure_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0004889C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• decreased brown fat cell lipid droplet size_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009125C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal hair growth_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0002073C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal coat/ hair morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000367C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• scaly skin_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001192C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• increased apoptosis_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0006042C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• thick dermal layer_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001245C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal hair follicle development_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0003704C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal keratohyalin granule morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009602C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• dilated hair follicle infundibulum_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0010683C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• dry skin_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0003853C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal epidermis stratum corneum morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001240C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal sphingomyelin level_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009823C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• enlarged sebaceous gland_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000652C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal awl hair morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000400C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• skin inflammation_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0004947C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal skin sebaceous gland morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009535C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal hair follicle infundibulum morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0010682C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal hair follicle bulge morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009759C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• increased eosinophil cell number_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0005011C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal ceramide level_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0012232C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• impaired skin barrier function_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0002796C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal hair shaft morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0003809C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• decreased inguinal fat pad weight_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009293C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• increased epididymal fat pad weight_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009288C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• increased basal metabolism_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0008965C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal sebocyte morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0013375C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal hair cuticle_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0003810C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• delayed skin barrier formation_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009441C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• hyperkeratosis_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001242C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal epidermis stratum granulosum morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001239C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• abnormal hair follicle morphology_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0000377C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• increased keratinocyte proliferation_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009583C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• epidermal hyperplasia_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0001222C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• decreased sphingosine level_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0020117C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi
• decreased epididymal fat pad weight_Acer1<tm1a(EUCOMM)Wtsi>/Acer1<tm1a(EUCOMM)Wtsi>
  http://metadb.riken.jp/0009289C57BL6NAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsiAcer1tm1aEUCOMMWtsi