Baihao. Zhang, et.al., Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model., Proceedings of the National Academy of Sciences of the United States of America, 2016, 113

http://rdf.ncbi.nlm.nih.gov/pubmed/27410049

Baihao. Zhang, et.al., Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model., Proceedings of the National Academy of Sciences of the United States of America, 2016, 113

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating lipase level_Foxp3<tm2.1(EGFP/cre)Shori>/Y,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0011887I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriYPdcd1tm1HonPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShori
• premature death_Foxp3<tm2.1(EGFP/cre)Shori>/Y,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0002083I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriYPdcd1tm1HonPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShori
• pancreas atrophy_Foxp3<tm2.1(EGFP/cre)Shori>/Y,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0013295I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriYPdcd1tm1HonPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShori
• increased effector memory T-helper cell number_Foxp3<tm2.1(EGFP/cre)Shori>/Y,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0013772I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriYPdcd1tm1HonPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShori
• abnormal spleen morphology_Foxp3<tm2.1(EGFP/cre)Shori>/Y,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0000689I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriYPdcd1tm1HonPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShori
• abnormal lymph node morphology_Foxp3<tm2.1(EGFP/cre)Shori>/Y,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0002339I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriYPdcd1tm1HonPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShori
• enlarged lymph nodes_Foxp3<tm2.1(EGFP/cre)Shori>/Y,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0000702I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriYPdcd1tm1HonPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShori
• pancreas inflammation_Foxp3<tm2.1(EGFP/cre)Shori>/Y,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0001869I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriYPdcd1tm1HonPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShori
• increased susceptibility to autoimmune disorder_Foxp3<tm2.1(EGFP/cre)Shori>/Y,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0005350I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriYPdcd1tm1HonPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShori
• decreased regulatory T cell number_Foxp3<tm2.1(EGFP/cre)Shori>/Y
  http://metadb.riken.jp/0004974I129C57BL6Foxp3tm21EGFPcreShoriYFoxp3tm21EGFPcreShori
• premature death_Foxp3<tm2.1(EGFP/cre)Shori>/Foxp3<tm2.1(EGFP/cre)Shori>,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0002083I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriFoxp3tm21EGFPcreShoriPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShoriPdcd1tm1Hon
• enlarged spleen_Foxp3<tm2.1(EGFP/cre)Shori>/Y,Pdcd1<tm1Hon>/Pdcd1<tm1Hon>
  http://metadb.riken.jp/0000691I129129S2SvPasC57BL6Foxp3tm21EGFPcreShoriYPdcd1tm1HonPdcd1tm1HonPdcd1tm1HonFoxp3tm21EGFPcreShori