Laura. Baroncelli, et.al., A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging., Human molecular genetics, 2016, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/27466184

Laura. Baroncelli, et.al., A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging., Human molecular genetics, 2016, 25

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• microgliosis_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0008918I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal long term object recognition memory_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0002801I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal synapse morphology_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0009538I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal long term object recognition memory_Slc6a8<tm1.1Lbar>/Y,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002801I129C57BL6C57BL6JC57BL6NSJLSlc6a8tm11LbarYTgNescre1Kln0TgNescre1KlnSlc6a8tm11Lbar
• impaired coordination_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0001405I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal object recognition memory_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0001458I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal short term object recognition memory_Slc6a8<tm1.1Lbar>/Y,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002800I129C57BL6C57BL6JC57BL6NSJLSlc6a8tm11LbarYTgNescre1Kln0TgNescre1KlnSlc6a8tm11Lbar
• abnormal dentate gyrus morphology_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0000812I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal neuron proliferation_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0009967I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal neuron proliferation_Slc6a8<tm1.1Lbar>/Y,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009967I129C57BL6C57BL6JC57BL6NSJLSlc6a8tm11LbarYTgNescre1Kln0TgNescre1KlnSlc6a8tm11Lbar
• abnormal object recognition memory_Slc6a8<tm1.1Lbar>/Y,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001458I129C57BL6C57BL6JC57BL6NSJLSlc6a8tm11LbarYTgNescre1Kln0TgNescre1KlnSlc6a8tm11Lbar
• abnormal spatial working memory_Slc6a8<tm1.1Lbar>/Y,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008428I129C57BL6C57BL6JC57BL6NSJLSlc6a8tm11LbarYTgNescre1Kln0TgNescre1KlnSlc6a8tm11Lbar
• abnormal GABAergic neuron morphology_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0003245I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal spatial reference memory_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0008414I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• decreased creatine level_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0010062I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• decreased creatine level_Slc6a8<tm1.1Lbar>/Y,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0010062I129C57BL6C57BL6JC57BL6NSJLSlc6a8tm11LbarYTgNescre1Kln0TgNescre1KlnSlc6a8tm11Lbar
• decreased hippocampus volume_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0020083I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal short term object recognition memory_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0002800I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal spatial working memory_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0008428I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• decreased body weight_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0001262I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• increased grooming behavior_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0001441I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar
• abnormal dentate gyrus morphology_Slc6a8<tm1.1Lbar>/Y,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000812I129C57BL6C57BL6JC57BL6NSJLSlc6a8tm11LbarYTgNescre1Kln0TgNescre1KlnSlc6a8tm11Lbar
• lipofuscinosis_Slc6a8<tm1.2Lbar>/Y
  http://metadb.riken.jp/0008842I129129S1SvC57BL6JC57BL6NSlc6a8tm12LbarYSlc6a8tm12Lbar