Marek. Vrbacký, et.al., Knockout of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice., Human molecular genetics, 2016, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/28173120

Marek. Vrbacký, et.al., Knockout of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice., Human molecular genetics, 2016, 25

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tmem70<tm1b(KOMP)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5897275

class

http://purl.org/net/cito/citesAsAuthority

• Tmem70<tm1b(KOMP)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5897275

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal mitochondrial physiology_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0006036IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• delayed heart development_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0012082IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• embryonic lethality during organogenesis, complete penetrance_Tmem70<tm1b(KOMP)Wtsi>/Tmem70<tm1b(KOMP)Wtsi>
  http://metadb.riken.jp/0011098IC57BL6NC57BL6NTacTmem70tm1bKOMPWtsiTmem70tm1bKOMPWtsiTmem70tm1bKOMPWtsi
• abnormal mitochondrial crista morphology_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0011635IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• delayed embryo turning_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0004188IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• embryonic lethality during organogenesis, complete penetrance_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0011098IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• disorganized mitochondrial cristae_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0011636IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• delayed rostral neuropore closure_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0012708IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• small heart_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0002188IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• oxidative stress_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0003674IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• decreased ventricle muscle contractility_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<+>
  http://metadb.riken.jp/0005598IC57BL6NTmem70tm1aKOMPWtsiTmem70Tmem70Tmem70tm1aKOMPWtsi
• abnormal enzyme/coenzyme level_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0005319IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• abnormal oxidative phosphorylation_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0010959IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• embryonic growth retardation_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0003984IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• decreased embryo size_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001698IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• delayed somite formation_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0003794IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi
• abnormal mitochondrial shape_Tmem70<tm1a(KOMP)Wtsi>/Tmem70<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0011633IC57BL6NTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsiTmem70tm1aKOMPWtsi