S. Winandy, et.al., A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma., Cell, 1995, 83

http://rdf.ncbi.nlm.nih.gov/pubmed/7585946

S. Winandy, et.al., A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma., Cell, 1995, 83

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal T cell differentiation_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002145I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• enlarged cervical lymph nodes_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0008542I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• increased spleen white pulp amount_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0008478I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• abnormal thymus lobule morphology_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002367I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• enlarged cervical lymph nodes_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0008542I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• spleen hyperplasia_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0000693I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• abnormal thymus medulla morphology_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002375I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• lymph node hyperplasia_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0008102I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• abnormal lymph node cortex morphology_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002343I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• premature death_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• lymph node hyperplasia_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0008102I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• increased T cell proliferation_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0005348I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• abnormal thymus lobule morphology_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002367I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• abnormal lymph node medulla morphology_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002348I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• abnormal thymocyte activation_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0003850I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• spleen hyperplasia_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0000693I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• abnormal thymus medulla morphology_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002375I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• increased spleen white pulp amount_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0008478I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• decreased spleen red pulp amount_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0008477I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• abnormal T cell differentiation_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002145I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• abnormal lymph node cortex morphology_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002343I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• thymus cortex hypoplasia_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0000711I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• enlarged thymus_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0000709I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• increased leukemia incidence_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002026I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• premature death_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002083I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• enlarged mesenteric lymph nodes_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0008466I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• enlarged thymus_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0000709I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• increased T cell proliferation_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0005348I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• abnormal thymocyte activation_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0003850I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• enlarged mesenteric lymph nodes_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0008466I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• increased leukemia incidence_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002026I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• thymus cortex hypoplasia_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0000711I129S4SvJaeBALBcIkzf1tm1KgeIkzf1Ikzf1tm1KgeIkzf1
• decreased spleen red pulp amount_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0008477I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge
• abnormal lymph node medulla morphology_Ikzf1<tm1Kge>/Ikzf1<+>
  http://metadb.riken.jp/0002348I129S4SvJaeC57BL6Ikzf1tm1KgeIkzf1Ikzf1Ikzf1tm1Kge

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD18587
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD18587