S W. Li, et.al., Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone., Genes & development, 1995, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/7590256

S W. Li, et.al., Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone., Genes & development, 1995, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col2a1<tm1Prc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2152978

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal bone marrow cavity morphology_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000065I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal head shape_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0011495I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal cartilage development_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000164I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• decreased body size_Col2a1<tm1Prc>/Col2a1<+>
  http://metadb.riken.jp/0001265I129SvC57BL6Col2a1tm1PrcCol2a1Col2a1tm1PrcCol2a1
• short limbs_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000547I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• short ribs_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0004672I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal cartilage development_Col2a1<tm1Prc>/Col2a1<+>
  http://metadb.riken.jp/0000164I129SvC57BL6Col2a1tm1PrcCol2a1Col2a1tm1PrcCol2a1
• perinatal lethality, complete penetrance_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0011089I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• increased renal plasma flow rate_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0005525I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal pulmonary alveolus morphology_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0002270I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• cleft palate_Col2a1<tm1Prc>/Col2a1<+>
  http://metadb.riken.jp/0000111I129SvC57BL6Col2a1tm1PrcCol2a1Col2a1tm1PrcCol2a1
• cleft palate_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000111I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal viscerocranium morphology_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0005274I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• decreased body size_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0001265I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• neonatal lethality, incomplete penetrance_Col2a1<tm1Prc>/Col2a1<+>
  http://metadb.riken.jp/0011088I129SvC57BL6Col2a1tm1PrcCol2a1Col2a1tm1PrcCol2a1
• abnormal head shape_Col2a1<tm1Prc>/Col2a1<+>
  http://metadb.riken.jp/0011495I129SvC57BL6Col2a1tm1PrcCol2a1Col2a1tm1PrcCol2a1
• kidney hemorrhage_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000533I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal chondrocyte morphology_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000166I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• decreased fetal size_Col2a1<tm1Prc>/Col2a1<+>
  http://metadb.riken.jp/0004200I129SvC57BL6Col2a1tm1PrcCol2a1Col2a1tm1PrcCol2a1
• decreased length of long bones_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0004686I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• short snout_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000445I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal long bone epiphysis morphology_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000131I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal chondrocyte morphology_Col2a1<tm1Prc>/Col2a1<+>
  http://metadb.riken.jp/0000166I129SvC57BL6Col2a1tm1PrcCol2a1Col2a1tm1PrcCol2a1
• abnormal autopod morphology_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000572I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• short snout_Col2a1<tm1Prc>/Col2a1<+>
  http://metadb.riken.jp/0000445I129SvC57BL6Col2a1tm1PrcCol2a1Col2a1tm1PrcCol2a1
• absent palatal shelf_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0009882I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal vertebral arch morphology_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0004599I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• small cranium_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0005352I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal limb bone morphology_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0002115I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• respiratory distress_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0001954I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• decreased bone mineral density_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000063I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc
• abnormal skeleton development_Col2a1<tm1Prc>/Col2a1<+>
  http://metadb.riken.jp/0002113I129SvC57BL6Col2a1tm1PrcCol2a1Col2a1tm1PrcCol2a1
• short limbs_Col2a1<tm1Prc>/Col2a1<+>
  http://metadb.riken.jp/0000547I129SvC57BL6Col2a1tm1PrcCol2a1Col2a1tm1PrcCol2a1
• abnormal heart valve morphology_Col2a1<tm1Prc>/Col2a1<tm1Prc>
  http://metadb.riken.jp/0000285I129SvC57BL6Col2a1tm1PrcCol2a1tm1PrcCol2a1tm1Prc

class

http://purl.org/net/cito/citesAsAuthority

• Col2a1<tm1Prc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2152978