P. Saftig, et.al., Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells., The EMBO journal, 1995, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/7641679

P. Saftig, et.al., Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells., The EMBO journal, 1995, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ctsd<tm1Cptr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182078

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0002083EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• abnormal intestinal mucosa morphology_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0000511EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• thymus hypoplasia_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0001823EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• abnormal ileum morphology_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0002581EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• decreased double-positive T cell number_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0005092EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• abnormal crypts of Lieberkuhn morphology_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0000490EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• decreased lymphocyte cell number_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0005016EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• abnormal thrombosis_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0005048EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• abnormal spleen white pulp morphology_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0002357EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• abnormal spleen B cell follicle morphology_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0008470EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• decreased body weight_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0001262EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• bradykinesia_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0005156EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr
• ataxia_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>
  http://metadb.riken.jp/0001393EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr

class

http://purl.org/net/cito/citesAsAuthority

• Ctsd<tm1Cptr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182078

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD39148
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39148