M. Ishibashi, et.al., Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects., Genes & development, 1995, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/8543157

M. Ishibashi, et.al., Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects., Genes & development, 1995, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hes1<tm1Fgu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2149672

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality during organogenesis, incomplete penetrance_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0011108I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• lethality throughout fetal growth and development, incomplete penetrance_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0011109I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• incomplete rostral neuropore closure_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0000928I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• anencephaly_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0001890I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• microcephaly_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0000433I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• perinatal lethality, complete penetrance_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0011089I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• everted embryonic neuroepithelium_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0012686I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• abnormal neuron differentiation_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0009937I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• abnormal neural tube morphology_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0002151I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• exencephaly_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0000914I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• abnormal brain development_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0000913I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu
• kinked neural tube_Hes1<tm1Fgu>/Hes1<tm1Fgu>
  http://metadb.riken.jp/0003400I129S1Sv129X1SvJCD1Hes1tm1FguHes1tm1FguHes1tm1Fgu

class

http://purl.org/net/cito/citesAsAuthority

• Hes1<tm1Fgu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2149672

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD02140
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02140
• CD06011
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD06011
• CD44727
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD44727
• CD03233
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03233
• CD16303
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16303
• CD03243
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03243

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• ICR;129-Hes1<tm1Fgu>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC05979

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• microcephaly in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008937
• perinatal lethality, complete penetrance in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008973
• abnormal neuron differentiation in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008969
• exencephaly in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008941
• kinked neural tube in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008954
• embryonic lethality during organogenesis, incomplete penetrance in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008974
• abnormal embryonic neuroepithelium morphology in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014604
• abnormal brain development in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008940
• everted embryonic neuroepithelium in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008976
• lethality throughout fetal growth and development, incomplete penetrance in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008975
• incomplete rostral neuropore closure in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008942
• anencephaly in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008946
• abnormal neural tube morphology in RBRC05979
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008948

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]